A Pilot Study Evaluating Quantitative Volume Contrast Enhanced Ultrasound (VCEUS) Imaging for Determining Early Breast Cancer Response to Neoadjuvant Chemotherapy
Interventional
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
VCEUS Quantitative Response vs grayscale US
Evaluate quantitative VCEUS imaging for determining early breast cancer response to neoadjuvant chemotherapy and compare results to co-temporal volume change on grayscale US, utilizing final surgical pathology and clinical outcome as reference standards. Specifically, changes in peak signal intensity and area under the curve will be compared with co-temporal changes in volume on grayscale US.
Post neoadjuvant therapy (aproximately 2-3 months after start of treatment)
No
Heidi R Umphrey, MD
Principal Investigator
University of Alabama at Birmingham
United States: Food and Drug Administration
R12-021
NCT01817374
March 2013
January 2015
Name | Location |
---|---|
University of Alabama at Birmingham | Birmingham, Alabama 35294-3300 |