PHASE II EVALUATION OF MR-GUIDED LASERINDUCED INTERSTITIAL THERMAL THERAPY (LITT) FOR PROSTATE CANCER
PRIMARY OBJECTIVES:
I. To evaluate the oncologic efficacy of laster interstitial thermal therapy (LITT) with
primary endpoint of undetectable cancer on magnetic resonance imaging (MRI)-guided biopsy of
treatment zone at 3 months following treatment.
SECONDARY OBJECTIVES:
I. To evaluate oncologic efficacy at 12 months following treatment based on biopsy of the
treatment zone.
II. To determine treatment-related safety and toxicity. III. To longitudinally assess
urinary and sexual function in the year following treatment.
OUTLINE:
Patients undergo MR-guided LITT.
After completion of study treatment, patients are followed up at 1, 3, and 12 months.
Interventional
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Undetectable cancer on MRI-guided biopsy of ablation zone following treatment
At 3 months
No
Aytekin Oto
Principal Investigator
University of Chicago Comprehensive Cancer Center
United States: Institutional Review Board
12-1841
NCT01792024
January 2013
Name | Location |
---|---|
University of Chicago Comprehensive Cancer Center | Chicago, Illinois 60637-1470 |