Analysis of Intersectin Expression in Primary Human Neuroblastomas
N/A
N/A
Both
Neuroblastoma
Trial Information
Analysis of Intersectin Expression in Primary Human Neuroblastomas
OBJECTIVES:
- To determine whether intersectin (ITSN1) proteins are present at elevated levels in
primary human tumor samples.
OUTLINE: Archived tumor tissue samples are analyzed for intersectin (ITSN1) expression by
western blot assays with enhanced chemilumiscence and exposed to X-ray film. The films are
scanned, and levels of ITSN1 signal are quantified by densitometry.
Inclusion Criteria
DISEASE CHARACTERISTICS:
- Diagnosed with neuroblastoma
- Banked primary tumor samples from patients with stage 1, 2, 3, and 4 disease
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- Not specified
Type of Study:
Observational
Study Design:
N/A
Outcome Measure:
ITSN1 is highly expressed in neuroblastoma tumors and plays an important role in the development/progression of these tumors
Safety Issue:
No
Principal Investigator
John P. O'Bryan, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Illinois
Authority:
United States: Federal Government
Study ID:
CDR0000706794
NCT ID:
NCT01407731
Start Date:
July 2011
Completion Date:
Related Keywords:
- Neuroblastoma
- disseminated neuroblastoma
- localized resectable neuroblastoma
- localized unresectable neuroblastoma
- stage 4S neuroblastoma
- Neuroblastoma
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