Inclusion Criteria:

1. Histologic proof of papillary-serous ovarian cancer or 1ary peritoneal
carcinomatosis.

2. Histological grade III.

3. Original disease in stage III.

4. ECOG performance status: 0-2.

5. Age: 20-80 years.

6. Previous chemotherapy with paclitaxel and carboplatin (only).

7. Previous cyto-reductive surgery.

8. Clinical Complete Response (both physically and by imaging).

9. CA 125 should be either normalized (in at least 50 patients) or while still in
decreasing values at monthly measurements.

10. CBC at normal values or with any toxicity at a grade limited to I by NCIC-CTC.

11. Liver and renal functions < 1.5 upper normal limits (UNL) by SMA.

12. The patient's signature on the informed consent.

Exclusion Criteria:

1. Mucinous type ovarian carcinoma.

2. Histological Grade I-II.

3. Current continuous treatment by steroids or by NSAIDs, or by anti-coagulants for "non
protocol" reasons.

4. Previous history of active peptic ulcer.

5. Current participation in any other treatment study.