Trial Information
Effect of Exercise Training on Angiogenesis and Cachexia in Lung Cancer Patients
Inclusion Criteria:
- Age 40-75 years
- Advanced NSCLC
- Eastern Cooperative Oncology Group performance status of 0 or 1
- Targeted therapy for at least 8 weeks
- Stable condition
Exclusion Criteria:
- Severe metastasis, cardiopulmonary or musculoskeletal conditions may affect
participation in exercise
- Do not understand the verbal or written instructions
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Outcome Measure:
Exercise capacity
Outcome Description:
Maximal oxygen consumption with Vmax229 Vastus lateral muscle oxygenation with NIRS
Outcome Time Frame:
8 weeks after the start of the intervention
Safety Issue:
No
Principal Investigator
Ying-Tai Wu, Ph.D
Investigator Role:
Principal Investigator
Investigator Affiliation:
National Taiwan University Hospital
Authority:
Taiwan: Department of Health
Study ID:
201003064R
NCT ID:
NCT01136083
Start Date:
September 2010
Completion Date:
August 2012
Related Keywords:
- Non-Small-Cell Lung Cancer
- Tumor
- Angiogenesis
- Exercise training
- VEGF
- Myostatin
- Cachexia
- Carcinoma, Non-Small-Cell Lung
- Lung Neoplasms