Trial Information

Multicenter Prospective Analysis of Treatment Outcome in Patients With Large Acoustic Neuromas

The current standard treatment of a large tumor of the balance nerve (acoustic neuroma or
vestibular schwannoma) is surgical resection. Complete removal of such tumor is associated
with significant risks of hearing loss and facial paralysis whereas incomplete removal of
the tumor is associated with significant risks of regrowth. Stereotactic radiation is a well
accepted therapy aiming at stopping the growth of smaller acoustic neuromas before their
sizes become large enough to cause problems. The purpose of our study is to determine
whether the combination of subtotal resection followed by stereotactic radiation of the
remnant can control large acoustic neuromas without the significant risks associated with
complete resection.