Inclusion Criteria:

- adult (> 18 years) male or female patient

- patient has biopsy-proven NSCLC or lung metastasis

- patient has been rejected for surgery and has been considered unfit for radiation
therapy

- each 6 cm or smaller in greatest diameter of tumor, by CT scan

- tumors are located at least 1 cm from trachea; main bronchi; esophagus; aorta; aortic
arch branches; pulmonary artery; and heart

- tumors are accessible by percutaneous route

- patient has Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or
2

- patient has platelet count > 100 x 109 /L and international normalized ratio ≤ 1.5

- patient has signed written informed consent prior to any study specific procedures.

Exclusion Criteria:

- patient is considered at high-risk for RF ablation due to major co-morbid medical
conditions

- patient has more than 3 tumors / lung

- patient has at least one tumor > 6 cm in greatest diameter

- tumor is associated with atelectasis or obstructive pneumonitis

- patient has renal failure requiring hemodialysis or peritoneal dialysis

- patient has active clinically serious infection

- patient has history of organ allograft

- patient has history of substance abuse or any medical, psychological or social
conditions that may interfere with his / her participation in the study or evaluation
of the study results

- patient is pregnant or breast-feeding

- patient has ECOG performance status > 2

- patient has platelet count ≤ 100 x 109 /L or international normalized ratio > 1.5.