Inclusion Criteria:

Screening:

- Patients with AML at initial diagnosis or at first relapse

- 18 years of age or older

- ECOG Performance Status 0-2

- Life expectancy of greater than 9 weeks

- Laboratory values within limits outlined in the protocol

- Women of child-bearing potential and men must agree to use adequate contraception
prior to study entry and for the duration of study participation

Prior to Cell Collections for Dendritic Cell Generation:

- Patients must have obtained complete remission with chemotherapy defined by the
absence of circulating blasts, and less then 5% blasts on bone marrow examination
following hematopoietic recovery

- Resolution of all chemotherapy related Grade III-IV toxicity as per CTC criteria 4.0

- Laboratory values as outlined in the protocol

- For patients with evidence of minimal residual disease prior to vaccination,
assessment of minimal residual disease status by cytogenetics or FISH will be
followed post vaccination

Prior to Post-Chemotherapy Immunotherapy:

- Resolution of all chemotherapy related grade III-IV toxicity

- Laboratory values as outlined in the protocol

- At least 2 doses of fusion vaccine produced

Exclusion Criteria:

Screening:

- Active or history of autoimmune disorders/conditions including Type 1 diabetes. Type
II diabetes, vitiligo or stable hyperthyroidism will not be considered exclusion
criteria

- HIV positive

- Significant cardiac disease characterized by symptomatic congestive heart failure,
unstable angina pectoris, clinically significant cardiac arrhythmia

- Pregnant women

- Individuals with a history of a different malignancy are ineligible except for
circumstances outlined in the protocol document

Prior to Cell Collection for Dendritic Cell Generation:

- Serious intercurrent illness such as infection requiring IV antibiotics, or
significant cardiac disease characterized by significant arrhythmia, ischemic
coronary disease or congestive heart failure

- Patients who choose to proceed with allogeneic or autologous transplant at the time
of remission will not be vaccinated and will come off study