Trial Information
Oligogenic Determinism of Colorectal Cancer
Inclusion Criteria:
- colorectal cancer (CRC) in two first degree relatives, one being diagnosed before 61
years of age
- CRC diagnosed before 51 years of age or advanced colorectal adenoma before 41 years
of age
- multiple primary CRCs in the same individual, the first being diagnosed before 61
years of age.
Exclusion Criteria:
- Lynch syndrome,
- adenomatous polyposis defined by more than 10 adenomas histologically proved,
- hamartomatous polyposis defined by one hamartoma histologically proved,
- absence of informed consent.
Type of Study:
Interventional
Study Design:
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Outcome Measure:
genetic variation assessment
Outcome Time Frame:
once
Safety Issue:
No
Principal Investigator
Thierry FREBOURG, Pr
Investigator Role:
Principal Investigator
Investigator Affiliation:
CHU de Rouen
Authority:
France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
Study ID:
2009/082/HP
NCT ID:
NCT01057953
Start Date:
January 2010
Completion Date:
January 2012
Related Keywords:
- Cancer
- Colo-Rectal Cancer
- Colorectal Neoplasms