Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taipei, Taiwan
We have been following a schedule of weekly low dose docetaxel (30 mg/m2 on days 1 and 8
every 3 weeks; 60 mg/m2 accumulated dose for each cycle) at our hospital in an effort to
achieve better tolerability. We therefore performed an exploratory study, by statistical
analyses, to investigate the efficacy and toxicity of such a low dose docetaxel schedule
compared to that of pemetrexed in patients with NSCLC who have failed previous chemotherapy.
Interventional
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Objective response rate
at least 3 cycles
Yes
Han-Pin Kuo
Principal Investigator
Chang Gung Memorial Hospital
Taiwan: Institutional Review Board
98-2587B
NCT01004601
March 2005
October 2008
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