Trial Information

Preoperative Oral Supplementation With Carbohydrate and Branched-chain Amino Acid-enriched Nutrient Improves Postoperative Quality of Life in Patients Undergoing a Hepatectomy

Patients with cirrhosis of the liver complicated with HCC are often in a state of protein
energy malnutrition. A limited number of studies have indicated an important role for
nutritional support in the surgical management of patients who have undergone hepatic
resection for HCC. In a preliminary study, we reported the clinical efficacy of
supplementation with branched-chain amino acids in a small number of patients with liver
cirrhosis who underwent hepatic surgery for HCC. The aims of this study are (1) to study the
benefit of branched-chain amino acids enriched nutrient-mixture by analyzing a variety of
clinical parameter, including laboratory data, the duration of hospitalization after the
surgery, and (2) To investigate the postoperative QOL in receiving peri-operatively
branched-chain amino acids enriched nutrient-mixture in patients who undergone the hepatic
management for HCC with chronic liver disease.