Trial Information
Clinical Investigations on Cytokin-Gradients in Hypo/Euthyroid Patients. Evaluation of Expression of Different Pro-and Anti-Inflammatory Cyto-/Chemokines in Skin Wounds After Surgery of Benign Goitres (Struma Multinodosa) or Malignant Diseases of Thyroid Gland (Papillary Thyroid Carcinoma) in Correlation to the Status of Wound Healing of the Neck Wound
Inclusion Criteria:
- Near total or total thyroidectomy because of struma multinodsa (nodular goiter) with
or without substitution of thyroid hormone after operation
- Total thyroidectomy because of papillary carcinoma of thyroid gland (T1/T2
carcinoma, N1, M0) with planned radio-ablative therapy (RAT) without or with rhTSH
Exclusion Criteria:
- Pat< 18 years
- Immune disease of thyroid gland (Graves disease)
- Severe immunodeficiency
- Immunosuppressive medication because of solid Organ transplantation
- Hepatitis A/B/C or HIV
- All exclusion criteria for any surgical procedure
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Masking: Open Label, Primary Purpose: Basic Science
Outcome Measure:
Evidence for different cytokine levels in euthyroid vs hypothyroid condition confirmed by bood serum samples
Outcome Time Frame:
21 days after surgery
Safety Issue:
Yes
Authority:
Germany: Ethics Commission
Study ID:
MHH-THY-WH-09
NCT ID:
NCT00929318
Start Date:
June 2009
Completion Date:
April 2010
Related Keywords:
- Thyroid Neoplasms
- Thyroid Carcinoma
- Neoplasms
- Carcinoma
- Thyroid Neoplasms
- Thyroid Diseases