Trial Information

Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children With Cancer

OBJECTIVES:

I. To utilize a standardized battery of age-appropriate neuropsychological and behavioral
tests in conjunction with Children's Oncology Group (COG) Phase III clinical trials to
evaluate cognitive, social, emotional, and behavioral functioning over time.

II. To institute procedures to ensure a consistent, streamlined, and efficient
administration of the neuropsychological/behavioral tests in a cooperative group setting in
order to maximize compliance with a standardized assessment battery conducted at 3
standardized timepoints.

OUTLINE:

Parent and child participants complete the COG Standard Neuropsychological and Behavioral
Battery testing at 9, 30, and 60 months post-diagnosis in a 1-hour session conducted by a
neuropsychologist or psychologist. The Battery consists of tests of intelligence, processing
speed/attention, memory, language preference, general developmental progress, attention and
behavior/social/emotional function, executive function, adoptive function, and quality of
life. Additionally, parents complete a parent-report questionnaire to gather information
about patient's function in terms of attention, memory, executive abilities, and behavioral,
social, and emotional adaption.