Impact of a Capsular Incision on Biochemical Recurrence After Radical Perineal Prostatectomy
43 Years
78 Years
Male
Radical Perineal Prostatectomy
Trial Information
Impact of a Capsular Incision on Biochemical Recurrence After Radical Perineal Prostatectomy
The pathological classification of the prostate following radical prostatectomy provides
important prognostic information; an accurate pathology report is the cornerstone to cancer
treatment and follow-up. In addition to the preoperative serum PSA, Gleason score on
pathology specimens, seminal vesicle invasion and lymph node status, and a positive surgical
margin with extraprostatic extension (EPE) are significant predictors of clinical and
biochemical recurrence. However, the prognostic implication of a capsular incision, a tumor
extending to the inked margins without a histologically documented EPE, remains to be
defined.
Inclusion Criteria:
- pathologically proven prostate cancer
- follow-up for at least 6 months
Exclusion Criteria:
- insufficient biopsy data
- seminal vesicle invasion or lymph node involvement on pathology
- neoadjuvant or adjuvant therapy
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Retrospective
Outcome Measure:
biochemical recurrence of prostate cancer
Outcome Time Frame:
upto the final date of study
Safety Issue:
No
Principal Investigator
han yong Choi, professor
Investigator Role:
Principal Investigator
Investigator Affiliation:
Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine
Authority:
Korea: Food and Drug Administration
Study ID:
SMC IRB 2008-08-012
NCT ID:
NCT00748514
Start Date:
June 1995
Completion Date:
January 2008
Related Keywords:
- Radical Perineal Prostatectomy
- capsular incision
- biochemical recurrence
- radical perineal prostatectomy
- Recurrence
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