Know Cancer

or
forgot password

Establishment of a Brain and Spinal Tumor Tissue Bank and Clinical Data Repository for Identifying Molecular Markers of Clinical Outcome


N/A
20 Years
N/A
Open (Enrolling)
Both
Glioblastoma Multiforme, Glioma, Neuroectodermal Tumors

Thank you

Trial Information

Establishment of a Brain and Spinal Tumor Tissue Bank and Clinical Data Repository for Identifying Molecular Markers of Clinical Outcome


Glioblastoma multiforme (GBM) is the most common and lethal primary Brain and Spinal Tumor
in adults. It is nearly uniformly fatal, with a median survival of approximately one year,
despite modern treatment modalities. Efforts to understand why some patients live longer or
shorter than the average may provide insights into the biology of these neoplasms. For
years, researchers have tried to identify independent predictors that could help in
treatment planning. With the recent interest in molecular biology and molecular genetics,
tumor markers are now being examined as potential predictors. A marker that could predict
tumor response to therapy, the likelihood of recurrence, and survival would thus be quite
useful.


Inclusion Criteria:



- Patients must have a suspected or confirmed diagnosis of Brain and Spinal Tumor

- Age greater than 20

- Signed consent

Exclusion Criteria:

- Known HIV infection

- Any other clinical condition which, in the opinion of the principal investigator,
would not allow completion of this study

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

Collect, annotate, and store fresh frozen specimens of normal tissue, tumors, and pre-malignant lesions for biological investigation.

Outcome Time Frame:

5 years

Safety Issue:

No

Principal Investigator

Kuo-Sheng Hung, MD, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Taipei Medical University-Wan Fang Hospital

Authority:

Taiwan: Department of Health

Study ID:

2008WFCRC-01

NCT ID:

NCT00686387

Start Date:

May 2008

Completion Date:

May 2013

Related Keywords:

  • Glioblastoma Multiforme
  • Glioma
  • Neuroectodermal Tumors
  • Tissue Bank
  • Glioblastoma Multiforme
  • NAT2
  • EGFR
  • MGMT
  • Brain and Spinal TumorGliomas
  • Glioblastoma
  • Glioma
  • Spinal Cord Neoplasms
  • Spinal Neoplasms
  • Neuroectodermal Tumors

Name

Location