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Prevention of Contrast Induced Nephropathy in Oncology Patients With Sodium Bicarbonate


N/A
18 Years
N/A
Not Enrolling
Both
Contrast Induced Nephropathy

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Trial Information

Prevention of Contrast Induced Nephropathy in Oncology Patients With Sodium Bicarbonate


Inclusion Criteria:



- > 18 years old

- cancer diagnosis

- GFR < 60 and > 30 ml/min/1,73m2 by MDRD formula or diabetic

- CT with contrast

Exclusion Criteria:

- dialysis needed

- uncontrolled hypertension

- changes in serum creatinine levels of at least 0.5 mg/dl during the previous 24 hours
of procedure

- recent exposure to radiographic contrast agents (within previous two days of the
study)

- administration of dopamine, mannitol , fenoldopam or N-Acetyl Cystein during the
intended time of study

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Outcome Measure:

Development of contrast-induced nephropathy, defined as an increase in serum creatinine of 25% or more within 2 day after administration of contrast or dialysis needed

Outcome Time Frame:

2 days

Safety Issue:

No

Principal Investigator

Ricardo G Silva, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Hospital do Cancer de Barretos - Fundação PIO XII

Authority:

Brazil: National Committee of Ethics in Research

Study ID:

1-Silva

NCT ID:

NCT00540904

Start Date:

September 2007

Completion Date:

September 2009

Related Keywords:

  • Contrast Induced Nephropathy
  • contrast
  • nephropathy
  • bicarbonate
  • prevention
  • Kidney Diseases

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