African American Families and Lung Cancer Study
The purpose of the African American (AA) Families and Lung Cancer Study is to learn more
about (1) the beliefs of family members of AA patients with lung cancer about why AA get
lung cancer and (2) whether these beliefs are associated with their interest in genetic
testing for lung cancer risk and willingness to participate in clinical genetics research.
We plan to recruit 200 AAs (n = 100 current smokers and n = 100 never smokers) who are
considered to be as close as family (both biological and non-biological kin) to patients
with lung cancer who self-identify as AA (n = 115). Patients will be recruited from
Washington Cancer Institute at the Washington Hospital Center in Washington, DC. Family
members who self-identify as AA and are between the ages 18 and 55 will be eligible for the
study. A Washington Hospital Center recruiter will approach patients and ask their
willingness to be contacted for a telephone survey about their general well-being. As part
of the survey, patients will be asked to enumerate family and friends who they consider to
be as close as family, and asked to specifically focus on those who are current cigarette
smokers and those who have never smoked. Patients will be asked to give permission to
contact some or all of those enumerated. These family members will be mailed a letter to
inform them that unless they call to decline they will be contacted by a telephone
interviewer. The survey will include questions to assess family members' explanations for
the causes of lung cancer and reactions to possible explanations for disparities in lung
cancer between AA and Caucasian Americans (CA), perceived personal risk and worry about
developing lung cancer, smoking history, motivation to quit smoking, emotional responses to
the patient's diagnosis, racial identity, experience with racial discrimination, pros and
cons of genetic testing, and interest in genetic testing (the primary outcome variable).
Data analysis using hierarchical linear modeling will assess whether patient characteristics
and family members' endorsement of genetics as the cause of lung cancer are associated with
their interest in genetic testing and participation in clinical genetics research.
Observational
Time Perspective: Prospective
United States: Federal Government
999907161
NCT00487760
June 2007
August 2011
Name | Location |
---|---|
Washington Hospital Center | Washington, District of Columbia 20010 |