Psychoneuroimmunology and Mind-Body Interventions
This study is designed to examine the effects of hatha yoga on autonomic, immune, and
endocrine function. The data from both inexperienced and experienced groups will help us
better understand how longer-term practice of yoga may be beneficial. The study consists of
one 3-hour screening session and three 6-hour activity sessions with 30 minute follow-up
appointments the following morning scheduled 2 - 4 weeks apart. Each participant will
complete the 3 activity sessions, which will consist of either yoga, mild movement, or a
neutral activity (watching a videotape), in randomly assigned order. Thus, both novices and
experts will participate in 3 activity sessions each (yoga, movement control, video
control). The order in which each participant goes through the activity sessions is
counterbalanced. Data for each activity session will be aggregated by group (i.e. novice or
expert). We will measure responses to tape stripping to assess skin barrier repair, and
evaluate responses to computer tasks, self-report measures, and a battery of unobtrusive
behavioral measures. We will also collect blood and saliva samples to measure immune and
endocrine outcomes.
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
Number of Participants With Detectable C-Reactive Protein (CRP)
High sensitivity C-reactive protein (hsCRP) assessed once at baseline, at each of the three visits. The hsCRP assay was performed using chemiluminescence methodology with the Immulite 1000 (Siemens Medical Solutions, Los Angeles, Ca.) The lowest level of detection is .3 mg/dL. 43% of the values were below this lower bound, thus hsCRP was dichotomized as undetectable/detectable.
8:30 a.m. at each of the three visits, scheduled at least 2 weeks apart
No
Janice K. Kiecolt-Glaser, PhD
Principal Investigator
Ohio State University
United States: Federal Government
2005H0068
NCT00371397
September 2005
September 2008
Name | Location |
---|---|
Ohio State University Clinical Research Center | Columbus, Ohio 43210 |