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A Cross-Sectional Study of Erectile Dysfunction in Patients With Locally Advanced Prostate Cancer Who Have Undergone Radiotherapy and Prolonged Pharmacological Androgen Ablation


Phase 2
18 Years
N/A
Not Enrolling
Male
Prostatic Neoplasms

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Trial Information

A Cross-Sectional Study of Erectile Dysfunction in Patients With Locally Advanced Prostate Cancer Who Have Undergone Radiotherapy and Prolonged Pharmacological Androgen Ablation


Inclusion Criteria:



- Patients with clinical stage T1-T4 carcinoma of the prostate

- Must have undergone radical radiation and at least 2 years of Pharmacological
androgen ablation.Pharmacological androgen ablation may include: LHRH-agonists with
or without Non-steroidal androgen ablation, Steroidal Anti-androgens, Progestational
agents, and Cypoterone (Androcur).

- Must be currently 6 months or more after their last injection of LHRH-agonists if it
was being given every 3 months or 4 months or more after their last injection, if it
was being given monthly. If the patient was on oral androgen ablation agent, they
must be off this medication for a period of at least 4 months.

- currently off hormonal therapy

- Able to sign the consent form and fill out questionnaire used in the study.

Exclusion Criteria:

- No patients who have been treated, or are currently being treated with Bicalutamide

- no previous orchidectomy.

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Educational/Counseling/Training

Outcome Measure:

This study is designed to address absolute incidence of erectile dysfunction, as measured by the International index of Erectile function.

Principal Investigator

Padraig Warde, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Princess Margaret Hospital, Canada

Authority:

Canada: Ethics Review Committee

Study ID:

UHN REB 01-0552-C

NCT ID:

NCT00242138

Start Date:

March 2000

Completion Date:

April 2004

Related Keywords:

  • Prostatic Neoplasms
  • Neoplasms
  • Prostatic Neoplasms
  • Erectile Dysfunction

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