A Study of the Effect of Neoadjuvant Bicalutamide (Casodex) on Tumour Hypoxia in Patients With Clinically Localized Prostate Cancer
Interventional
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
To determine the effect of neoadjuvant anti-androgen therapy on oxygenation of prostatic tumours, and to correlate with changes in PSA, hemoglobin level, and prostate volume.
Michael Milosevic, MD
Principal Investigator
Princess Margaret Hospital, Canada
Canada: Ethics Review Committee
UHN REB 00-0430-C
NCT00188708
April 2001
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