35 Years
50 Years
Female
Endometriosis
Trial Information
Eutopic endometrium was obtained and separated into single endometrial stromal cell (ESC) in
women with adenomyosis (study group) and without adenomyosis (control group).
After becoming pre-confluent (covering 80% of the culture well), ESC was cultured for 8 days
solely or with the addition of medroxyprogesterone (MPA) or danazol.
ELISA was done to measure IL-6, IL-8, and TNF-alpha concentrations of the culture media.
Real-time quantitative RT-PCR was done to measure IL-6, IL-8, and TNF-alpha RNA levels in
ESC.
Inclusion Criteria:
- women with adenomyosis
- at early- to mid-secretory phases
Exclusion Criteria:
- postmenopausal
- malignancy
Type of Study:
Observational
Study Design:
Observational Model: Defined Population, Observational Model: Natural History, Time Perspective: Cross-Sectional, Time Perspective: Prospective
Principal Investigator
Jehn-Hsiahn Yang, M.D.
Investigator Role:
Principal Investigator
Investigator Affiliation:
Department of Obstetrics and Gynecology, National Taiwan University Hospital
Authority:
Taiwan: Department of Health
Study ID:
9361700762
NCT ID:
NCT00155051
Start Date:
July 2004
Completion Date:
April 2005
Related Keywords:
- Endometriosis
- Endometriosis
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