Know Cancer

or
forgot password

The Effect of PPARgamma Stimulation on Glucose Metabolism, Insulin Resistance, Growth Hormone and Cortisol on Women Suffering From Polycystic Ovary Syndrome


Phase 4
18 Years
45 Years
Not Enrolling
Female
Polycystic Ovary Syndrome

Thank you

Trial Information

The Effect of PPARgamma Stimulation on Glucose Metabolism, Insulin Resistance, Growth Hormone and Cortisol on Women Suffering From Polycystic Ovary Syndrome


Inclusion Criteria:



- Irregular menses, i.e. cyclus length of >36 days

- Premenopausal

- Increased fasting insulin > 50 pmol/l

- Increased free testosterone > 0.035 nmol/l

Exclusion Criteria:

- Age: <18 years

- Contraceptive pill within the past 3 months

- Postmenopausal (increased FSH)

- Known diabetes mellitus, endocrine disease or other disease requiring treatment

- Drug use

- Pregnancy

- Planned pregnancy during the treatment period

- Increased liver parameters

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Outcome Measure:

Glucose infusion rate (M value) below euglycaemic hyperinsulinaemic clamp (comparing baseline with 4 months)

Principal Investigator

Dorte Glintborg, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Odense University Hospital

Authority:

Denmark: National Board of Health

Study ID:

032

NCT ID:

NCT00145340

Start Date:

September 2002

Completion Date:

January 2007

Related Keywords:

  • Polycystic Ovary Syndrome
  • polycystic ovary syndrome (PCOS)
  • PPARgamma
  • growth hormone
  • insulin resistance
  • pioglitazone
  • glucose metabolism
  • microarray
  • Insulin Resistance
  • Polycystic Ovary Syndrome

Name

Location