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Alopecia Areata Registry and Immunogenetic Mechanisms

Open (Enrolling)
Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Autoimmune Hair Loss, Alopecia Partialis

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Trial Information

Alopecia Areata Registry and Immunogenetic Mechanisms

Alopecia areata is a condition in which hair is lost either from part of the scalp, all of
the scalp, or the entire body, and it affects 1% to 2% of the population. It is thought to
be an autoimmune disease and in some cases the disease is hereditary. The Alopecia Areata
Registry will collect information and blood samples from clinically well-characterized
patients with these three forms of alopecia areata: alopecia partialis (patchy loss of the
scalp hair), alopecia totalis (total loss of all scalp hair), and alopecia universalis
(complete loss of all hair everywhere on the body). This will be a collection of patients in
multi-generational families, twins, single patients with patchy, persistent transient
alopecia areata or long-standing alopecia totalis/universalis and with controls (persons
unaffected and not related to alopecia patients). Information from these patients will be
used to search the human genome for disease-associated loci and/or genes. Researchers
interested in doing pathophysiology or treatment studies of this disease will also be able
to contact patients having the appropriate form of the disease for the studies in question.

Patients who have been diagnosed with alopecia areata by a dermatologist will be eligible
for the registry. Patients will fill out an information form online
( Patients who have a family history or specific types of
alopecia will be invited to participate in a more detailed questionnaire and physical exam
and have blood samples drawn.

Inclusion Criteria

Inclusion Criteria

- Diagnosed with alopecia areata by a dermatologist

- United States resident

Accepts Health Volunteers: Non blood-related individuals who are unaffected with alopecia
areata and do not live in the same household with alopecia areata patient.

Type of Study:


Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Outcome Measure:

Alopecia Areata Registry

Outcome Description:

Database registration of participants via collection of participant epidemiology data.

Outcome Time Frame:

Registration on-going

Safety Issue:


Principal Investigator

Madeleine Duvic, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

M.D. Anderson Cancer Center


United States: Federal Government

Study ID:




Start Date:

November 2001

Completion Date:

November 2099

Related Keywords:

  • Alopecia Areata
  • Alopecia Totalis
  • Alopecia Universalis
  • Autoimmune Hair Loss
  • Alopecia Partialis
  • Baldness
  • Autoimmunity
  • Hair
  • Alopecia Areata
  • Alopecia Partialis
  • Alopecia Totalis
  • Alopecia Universalis
  • Autoimmune Hair Loss
  • Alopecia
  • Alopecia Areata



University of Minnesota Minneapolis, Minnesota  55455
Columbia University New York, New York  10032-3784
University of California, San Francisco San Francisco, California  94143
M.D. Anderson Cancer Center Houston, Texas  77030
University of Colorado - UCHSC - Health Science Center at Fitzsimons Aurora, Colorado  80010-7163