Know Cancer

forgot password

Differences in Parental Caregiving Demands in Childhood Acute Lymphoblastic Leukemia by Length of Infusion Therapy

Not Enrolling

Thank you

Trial Information

Differences in Parental Caregiving Demands in Childhood Acute Lymphoblastic Leukemia by Length of Infusion Therapy


- Compare the caregiving demands reported by parents of children with acute lymphoblastic
leukemia receiving methotrexate on 2 different infusion schedules (inpatient care vs
outpatient care).

- Compare the change in caregiving demands on these parents over time, in terms of
physical and emotional care, the need to make family arrangements, the need to
communicate about the child's care, the need to gather information about the child's
health status, and the effect on family well-being.

OUTLINE: Participants complete questionnaires regarding caregiver demands and family
information over 25-30 minutes within 3-4 months of the initiation of the child's treatment
and at the completion of the first year of the child's treatment.

PROJECTED ACCRUAL: A total of 164 participants will be accrued for this study within 0.8

Inclusion Criteria


- Parent or legal guardian who is the primary caregiver of a patient enrolled on
COG-P9904 or COG-P9905 protocol

- Patient has not yet received week 13 of therapy



- Not specified

Performance status

- Not specified

Life expectancy

- Not specified


- Not specified


- Not specified


- Not specified


- Able to understand English


Biologic therapy

- Not specified


- Not specified

Endocrine therapy

- Not specified


- Not specified


- Not specified

Type of Study:


Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Event Free Survival

Outcome Time Frame:

Length of study

Safety Issue:


Principal Investigator

Diane Keegan Wells, RN, MSN, CPNP

Investigator Role:

Study Chair

Investigator Affiliation:

University of Maryland Greenebaum Cancer Center


United States: Federal Government

Study ID:




Start Date:

December 2002

Completion Date:

March 2010

Related Keywords:

  • Leukemia
  • psychosocial effects of cancer and its treatment
  • childhood acute lymphoblastic leukemia
  • Leukemia
  • Leukemia, Lymphoid
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma



University of Mississippi Medical Center Jackson, Mississippi  39216-4505
Duke Comprehensive Cancer Center Durham, North Carolina  27710
Tripler Army Medical Center Honolulu, Hawaii  96859-5000
CCOP - Wichita Wichita, Kansas  67214-3882
Children's Hospital of Michigan Detroit, Michigan  48201
Hurley Medical Center Flint, Michigan  48503
Rhode Island Hospital Providence, Rhode Island  02903
Medical City Dallas Hospital Dallas, Texas  75230
University of Texas Health Science Center at San Antonio San Antonio, Texas  78284-7811
Midwest Children's Cancer Center Milwaukee, Wisconsin  53226
Van Elslander Cancer Center at St. John Hospital and Medical Center Grosse Pointe Woods, Michigan  48236
Natalie Warren Bryant Cancer Center at St. Francis Hospital Tulsa, Oklahoma  74136
Massachusetts General Hospital Cancer Center Boston, Massachusetts  02114
Comprehensive Cancer Center at Wake Forest University Winston-Salem, North Carolina  27157-1082
University of Texas Medical Branch Galveston, Texas  77555-1329
St. Vincent Hospital Green Bay, Wisconsin  54307-3508
University of Miami Sylvester Comprehensive Cancer Center Miami, Florida  33136
Rush University Medical Center Chicago, Illinois  60612-3824
UMASS Memorial Cancer Center - University Campus Worcester, Massachusetts  01605-2982
Keesler Medical Center - Keesler Air Force Base Keesler AFB, Mississippi  39534-2576
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire  03756-0002
Long Island Cancer Center at Stony Brook University Hospital Stony Brook, New York  11790-7775
CCOP - Columbia River Oncology Program Portland, Oregon  97225
CCOP - Scott and White Hospital Temple, Texas  76508
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland  21231-2410
Cancer Research Center of Hawaii Honolulu, Hawaii  96813
MBCCOP - LSU Health Sciences Center New Orleans, Louisiana  70112
Madigan Army Medical Center Tacoma, Washington  98431-5048
Sutter Cancer Center Sacramento, California  95816
Hackensack University Medical Center Hackensack, New Jersey  07601
Rebecca and John Moores UCSD Cancer Center La Jolla, California  92093-0658
University of California Davis Cancer Center Sacramento, California  95817
Children's Hospital of Southwest Florida Fort Myers, Florida  33908
Joe DiMaggio Children's Hospital at Memorial Hollywood, Florida  33021
Nemours Children's Clinic Jacksonville, Florida  32207
Miami Children's Hospital Miami, Florida  33155-4069
Florida Hospital Cancer Institute Orlando, Florida  32804
Sacred Heart Children's Hospital Pensacola, Florida  32504
All Children's Hospital St. Petersburg, Florida  33701
Children's Memorial Hospital - Chicago Chicago, Illinois  60614
Advocate Hope Children's Hospital Oak Lawn, Illinois  60453
Saint Jude Midwest Affiliate Peoria, Illinois  61637
Wesley Medical Center Wichita, Kansas  67214
Children's Hospital of New Orleans New Orleans, Louisiana  70118
Maine Children's Cancer Program Scarborough, Maine  04074-9308
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute Boston, Massachusetts  02115
Floating Hospital for Children Boston, Massachusetts  02111
Cardinal Glennon Children's Hospital Saint Louis, Missouri  63104
University of New Mexico Cancer Research and Treatment Center Albuquerque, New Mexico  87131
Schneider Children's Hospital New Hyde Park, New York  11042
St. Christopher's Hospital for Children Philadelphia, Pennsylvania  19134-1095
Children's Hospital of Greenville Hospital System Greenville, South Carolina  29605
St. Jude Children's Research Hospital Memphis, Tennessee  38105-2794
Driscoll Children's Hospital Corpus Christi, Texas  78466
Cook Children's Medical Center - Fort Worth Fort Worth, Texas  76104
Inova Fairfax Hospital Falls Church, Virginia  22042-3300
St. Louis Children's Hospital Saint Louis, Missouri  63110
Arizona Cancer Center at University of Arizona Health Sciences Center Tucson, Arizona  85724
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences Little Rock, Arkansas  72205
Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center Kansas City, Kansas  66160-7353
Tulane Cancer Center at Tulane University Hospital and Clinic New Orleans, Louisiana  70112
Blumenthal Cancer Center at Carolinas Medical Center Charlotte, North Carolina  28232-2861
Oklahoma University Medical Center Oklahoma City, Oklahoma  73104
Stanford Cancer Center at Stanford University Medical Center Stanford, California  94305
Wilford Hall Medical Center Lackland Air Force Base, Texas  78236-5300
Comprehensive Cancer Center at University of Alabama at Birmingham Birmingham, Alabama  35294
Children's Hospital and Health Center - San Diego San Diego, California  92123-4282
Broward General Medical Center Cancer Center Ft. Lauderdale, Florida  33316
University of Florida Shands Cancer Center Gainesville, Florida  32610-0232
Baptist-South Miami Regional Cancer Program Miami, Florida  33176
Nemours Children's Clinic - Orlando Orlando, Florida  32806
Kaplan Cancer Center at St. Mary's Medical Center West Palm Beach, Florida  33407
Via Christi Cancer Center at Via Christi Regional Medical Center Wichita, Kansas  67214
Ochsner Cancer Institute at Ochsner Clinic Foundation New Orleans, Louisiana  70121
Mount Sinai Medical Center New York, New York  10029
SUNY Upstate Medical University Hospital Syracuse, New York  13210
Mission Hospitals - Memorial Campus Asheville, North Carolina  28801
Presbyterian Cancer Center at Presbyterian Hospital Charlotte, North Carolina  28233-3549
Legacy Emanuel Hospital and Health Center & Children's Hospital Portland, Oregon  97227
Hollings Cancer Center at Medical University of South Carolina Charleston, South Carolina  29425
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas Dallas, Texas  75390
Naval Medical Center - Portsmouth Portsmouth, Virginia  23708-2197
Massey Cancer Center at Virginia Commonwealth University Richmond, Virginia  23298-0037
West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division Charleston, West Virginia  25302
Mary Babb Randolph Cancer Center at West Virginia University Hospitals Morgantown, West Virginia  26506
CCOP - Marshfield Clinic Research Foundation Marshfield, Wisconsin  54449
James P. Wilmot Cancer Center at University of Rochester Medical Center Rochester, New York  14642
Vermont Cancer Center at University of Vermont Burlington, Vermont  05405-0075
Greenebaum Cancer Center at University of Maryland Medical Center Baltimore, Maryland  21201
Kaiser Permanente Medical Center - Santa Clara Kiely Campus Santa Clara, California  95051-5386
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus Atlanta, Georgia  30342
Carilion Medical Center for Children at Roanoke Community Hospital Roanoke, Virginia  24014
University of South Alabama Cancer Research Institute Mobile, Alabama  36604
MBCCOP-Medical College of Georgia Cancer Center Augusta, Georgia  30912-4000
East Tennessee State University Cancer Center at Johnson City Medical Center Johnson City, Tennessee  37604
MBCCOP - South Texas Pediatrics San Antonio, Texas  78229-3900
Center for Cancer Prevention and Care at Scott and White Clinic Temple, Texas  76508
Kaiser Permanente Medical Center - Kaiser Foundation Hospital - San Diego San Diego, California  92120
Yale Comprehensive Cancer Center at Yale University School of Medicine New Haven, Connecticut  06520-8064
St. Joseph's Children's Hospital of Tampa Tampa, Florida  33677-4227
Pediatric Specialty Clinic at Eastern Maine Medical Center Bangor, Maine  04401
Walter Reed Army Medical Center Silver Spring, Maryland  20910
University of Missouri - Columbia Columbia, Missouri  65203
Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital Greenville, North Carolina  27858-4354
University of Virginia Cancer Center Charlottesville, Virginia  22908
Beth Israel Medical Center - Singer Division New York, New York  10128
Texas Children's Cancer Center and Hematology Service at Texas Children's Hospital Houston, Texas  77030-2399