Inclusion Criteria:

1. Diagnosis of histologically documented, advanced stage, primary or metastatic adult
solid tumors that are refractory to standard therapy or for which no curative
standard therapy exists. This includes but is not limited to cancers of the breast,
ovary, head and neck, esophagus, lung, gastrointestinal tract, and sarcomas.

2. Evidence of radiographically measurable or evaluable disease.

Exclusion Criteria:

1. Pre-existing peripheral neuropathy of CTC Grade > 2 due to any cause.

2. Documented hypersensitivity reaction (CTC Grade > 2) to prior paclitaxel or other
therapy containing Cremophor.