Selenium and Vitamin E Cancer Prevention Trial (SELECT) for Prostate Cancer
- Compare the effect of selenium and vitamin E administered alone vs in combination on
the clinical incidence of prostate cancer.
- Compare the effect of these prevention regimens on the incidence of lung cancer,
colorectal cancer, and all cancers combined in participants on this study.
- Compare the effect of these prevention regimens on prostate cancer-free survival, lung
cancer-free survival, colorectal cancer-free survival, cancer-free survival, overall
survival, and serious cardiovascular events in these participants.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
Number of Participants With Prostate Cancer
Participants are seen at the study site every six month for an update of medical events. Prostate cancer diagnosis is based on participant report followed by the submission of a pathologic sample to central pathology review for confirmation.
Every six months for 7 to 12 years depending on when the participant was randomized.
Eric Klein, MD
The Cleveland Clinic
United States: Federal Government
|Cardinal Bernardin Cancer Center at Loyola University Medical Center
|Maywood, Illinois 60153-5500
|Geisinger Medical Center
|Danville, Pennsylvania 17822-0001
|Geisinger Medical Group - Scenery Park
|State College, Pennsylvania 16801
|Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
|Wilkes-Barre, Pennsylvania 18711
|CCOP - Cancer Research for the Ozarks
|Springfield, Missouri 65807
|St. John's Regional Health Center
|Springfield, Missouri 65804
|Tod Children's Hospital
|Youngstown, Ohio 44501
|Robert H. Lurie Comprehensive Cancer Center at Northwestern University
|Chicago, Illinois 60611
|Midwest Center for Hematology/Oncology
|Joliet, Illinois 60432
|LaFortune Cancer Center at St. John Medical Center
|Tulsa, Oklahoma 74104
|Bethesda North Hospital
|Cincinnati, Ohio 45242
|U.T. Cancer Institute at University of Tennessee Medical Center
|Knoxville, Tennessee 37920-2911
|Good Samaritan Hospital Cancer Treatment Center
|Cincinnati, Ohio 45220