Inclusion Criteria

DISEASE CHARACTERISTICS: Histologically confirmed ovarian carcinoma Must be scheduled for
surgical evaluation

PATIENT CHARACTERISTICS: Age: Over 18 Performance status: Karnofsky 60-100% Life
expectancy: Greater than 12 weeks Hematopoietic: Absolute neutrophil count at least
1,500/mm3 Platelet count at least 100,000/mm3 No coagulation disorders Hepatic: Bilirubin
less than 2.0 mg/dL AST and ALT less than 2.5 times upper limit of normal Renal:
Creatinine less than 2.0 mg/dL Cardiovascular: LVEF greater than 50% No New York Heart
Association class III or IV heart disease No abnormalities on ECG that would preclude
study Pulmonary: FEV1 and FVC greater than 70% predicted No severe debilitating pulmonary
disease Other: No concurrent active infection requiring antibiotic therapy No concurrent
medical problem that would preclude study No prior autoimmune hepatitis or autoimmune
disease No psychiatric, addictive, or other disorder that would preclude consent

PRIOR CONCURRENT THERAPY: Biologic therapy: At least 4 weeks since prior immunotherapy and
recovered Chemotherapy: At least 4 weeks since prior chemotherapy and recovered Endocrine
therapy: Recovered from prior endocrine therapy Radiotherapy: At least 4 weeks since prior
radiotherapy and recovered Surgery: See Disease Characteristics Other: No concurrent
immunosuppressive therapy during the first 30 days after treatment