Inclusion Criteria

DISEASE CHARACTERISTICS: Histologically confirmed unresectable or metastatic cancer
Confirmed by biopsy or fine needle aspiration Tumors must predominantly involve the lung
Measurable or evaluable disease No lymphomas or leukemias No AIDS associate Kaposi's
Sarcoma No uncontrolled brain metastases

PATIENT CHARACTERISTICS: Age: 18 and over Performance status: SWOG 0-1 Life expectancy: At
least 3 months Hematopoietic: WBC at least 4,000/mm3 Platelet count within normal limits
Hepatic: Bilirubin no greater than 2 times normal Renal: Creatinine no greater than 2.0
mg/dL Cardiovascular: Adequate cardiovascular system with NYHA Class 0 or I No
uncontrolled cardiac arrhythmias Pulmonary: FEV1 at least 65% of predicted FVC at least
65% of predicted No asthma or bronchial obstruction that would prevent the delivery of
IL-2 to all lobes of the lung Other: HIV negative No medical or psychological criteria
that would make patient unable to tolerate the treatment Not pregnant or nursing Adequate
contraception required of all fertile patients

PRIOR CONCURRENT THERAPY: Biologic therapy: No prior interleukin-2 Prior biologic response
therapy allowed No chronic use of immunosuppressive medicines Chemotherapy: Prior
chemotherapy allowed Endocrine therapy: No chronic steroid use Prior hormonal therapy
allowed Radiotherapy: No prior or concurrent radiotherapy except as palliative to areas of
painful metastases outside the lung Surgery: Not specified