Leukemia, Lymphocytic, Chronic, B-Cell

Rheumatoid Arthritis

Solid Tumors and Advanced Endometrial Cancer, Endometrial Cancer, Second-line Treatment, VEGF

Prostate Cancer

Prostate Cancer, Metastatic (Spread to Other Areas of the Body)

Acute Myeloid Leukemia

Pulmonary Coin Lesion

B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, Cognitive/Functional Effects, Neurotoxicity, Pain, Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia, Therapy-related Toxicity, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia

Lung Cancer

Metastatic Renal Cell Carcinoma, Metastatic Melanoma

Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer

Pancreatic Cancer

Breast Cancer

Posterior Fossa Hemorrhage, Lung Cancer, Flank Pain, Urolithiasis, Focal Hepatic Necrosis

Acute Lymphoblastic Leukemia (ALL)

Breast Cancer

Soft Tissue Sarcoma

Heavy Uterine Bleeding, Uterine Fibroids

Solid Tumors, Hepatic Impairment

Nausea, Vomiting, Glioma

Non-small Cell Lung Cancer

Multiple Myeloma

Advanced Solid Tumors

Pancreatic Cancer

Childhood Cancer

Breast Cancer

Glioblastoma, Small Cell Glioblastoma, Giant Cell Glioblastoma, Gliosarcoma, Glioblastoma With Oligodendroglial Component

Relapsed Peripheral T-Cell Lymphoma, Refractory Peripheral T-Cell Lymphoma

Prostate Cancer

Solid Tumors

Non-Hodgkin's Lymphoma

Recurrent Supratentorial Glioblastoma Multiforme, GBM, Glioblastoma Multiforme

Locally Recurrent Breast Cancer, Metastatic Breast Cancer

Breast Cancer

Mantle-Cell Lymphoma

Glioblastoma, Small Cell Glioblastoma, Giant Cell Glioblastoma, Gliosarcoma, Glioblastoma With Oligodendroglial Component, Recurrent Glioblastoma, Relapsed Glioblastoma

Melanoma

Metastatic Breast Cancer

Metastatic Colorectal Cancer, Colorectal Cancer

Lambert-Eaton Myasthenic Syndrome, Eaton-Lambert Myasthenic Syndrome

Prostate Cancer

Childhood Mixed Glioma, Untreated Childhood Anaplastic Astrocytoma, Untreated Childhood Brain Stem Glioma, Untreated Childhood Giant Cell Glioblastoma, Untreated Childhood Glioblastoma, Untreated Childhood Gliosarcoma

Melanoma

HER2+ Cancer

Mild or Moderate Surgical Bleeding

Metastatic Breast Cancer

BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Primary Peritoneal Cavity Cancer

Cord Blood Transplant, Hematologic Malignancy, Inherited Metabolic Disease

Dose Escalation, Safety, Preliminary Efficacy, Advanced Solid Tumors, Metastatic Breast Cancer, Advanced Pancreatic Adenocarcinoma, Metastatic Colorectal Cancer, Recurrent Glioblastoma Multiforme

Carcinoid Tumor of the Small Bowel, Neuroendocrine Tumour

Advanced Renal Cell Carcinoma, Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma

Neuroblastoma

Neuroblastoma

B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Diffuse Large Cell Lymphoma, L3 Childhood Acute Lymphoblastic Leukemia, Stage III Childhood Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Untreated Childhood Acute Lymphoblastic Leukemia

Metastatic Breast Cancer

Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, Burkitt's Lymphoma, Follicular Lymphoma, Hodgkin Lymphoma, Mantle Cell Lymphoma

Neuroblastoma

Obesity, Overweight

Ovarian Cancer

Cytomegalovirus Infections

Solid Tumors

Hematological Malignancies

Cancer of the Cervix, Cervical Neoplasms

Grade IV Malignant Glioma

Squamous Cell Non-small Cell Lung Cancer

Stage IV Pancreatic Cancer

Multiple Myeloma

Metastatic Colorectal Cancer

Prostate Cancer

Advanced or Metastatic (Medically or Surgically Unresectable) Clear-cell Renal Cell Carcinoma

Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer

Breast Neoplasms