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  • cancer clinical trials in durham, NC

  • Study for Women With Platinum Resistant Ovarian Cancer Evaluating EC145 in Combination With Doxil® (PROCEED)
    Duke University Medical Center
    Durham, North Carolina 27710
    Ovarian Cancer
    A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis
    Duke University
    Durham, North Carolina 27710
    Estrogen Receptor Negative (ER-Negative) Breast Cancer, Progesterone Receptor Negative (PR-Negative) Breast Cancer, Human Epidermal Growth Factor Receptor 2 Negative (HER2-Negative) Breast Cancer, Brain Metastases
    Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid Leukemia
    Duke University Medical Center
    Durham, North Carolina 27710
    Acute Myeloid Leukemia
    Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)
    Duke University
    Durham, North Carolina 27710
    Diffuse Intrinsic Pontine Glioma
    A Study in Second Line Metastatic Colorectal Cancer
    For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    Durham, North Carolina
    Colorectal Cancer
    Optimal Type of Aerobic Training in Breast Cancer
    Duke Center for Living
    Durham, North Carolina 27710
    Breast Cancer
    Gliadel, XRT, Temodar, Avastin Followed by Avastin, Temodar for Newly Diagnosed Glioblastoma Multiforme (GBM)
    The Preston Robert Tisch Brain Tumor Center
    Durham, North Carolina 27710
    Glioblastoma Multiforme, Gliosarcoma
    Natural History Study of SCID Disorders
    Duke University
    Durham, North Carolina 27710
    SCID, Leaky SCID, Omenn Syndrome, Reticular Dysgenesis, ADA Deficiency, XSCID
    Reduced Radiation in Patients With Diffuse Large B-cell Lymphoma
    Durham Regional Hospital

    Trial Locations
    Durham Regional Hospital
    Duke University Medical Center
    Diffuse Large B-cell Lymphoma
    Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection
    Duke University Medical Center
    Durham, North Carolina 27710
    Bacteremia
    Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Clear Cell Ovarian Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Ovarian Clear Cell Cystadenocarcinoma, Stage III Ovarian Epithelial Cancer, Stage IV Ovarian Epithelial Cancer
    A Study in Patients With Rheumatoid Arthritis
    For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    Durham, North Carolina
    Rheumatoid Arthritis
    Study Of Abraxane® And Carboplatin As First-Line Treatment For Triple Negative Metastatic Breast Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Metastatic Breast Cancer
    PONATINIB for Chronic Myeloid Leukemia (CML) Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL)
    Duke University Medical Center, Site #003
    Durham, North Carolina 27710
    Chronic Myeloid Leukemia (CML), Ph+ Acute Lymphoblastic Leukemia (ALL)
    A Study Combining LY2157299 With Temozolomide-based Radiochemotherapy in Patients With Newly Diagnosed Malignant Glioma
    For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    Durham, North Carolina
    Glioma
    Pilot Study Evaluating Safety & Efficacy of DCBT: NiCord® & UNM CBU to Patients With Hematological Malignancies
    Duke University Medical Center
    Durham, North Carolina 27710
    Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML), Myelodysplastic Syndrome (MDS), Non-Hodgkin's Lymphoma, Hodgkin's Disease
    Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Adult Rhabdomyosarcoma, Alveolar Childhood Rhabdomyosarcoma, Mixed Childhood Rhabdomyosarcoma, Pleomorphic Childhood Rhabdomyosarcoma, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Adult Soft Tissue Sarcoma, Recurrent Childhood Rhabdomyosarcoma
    CMR Rate of Newly Diagnosed CML-CP Patients Treated With Nilotinib
    Duke University Medical Center Duke University Med Ctr
    Durham, North Carolina 27710
    Chronic Myelogenous Leukemia in Chronic Phase
    Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Childhood Supratentorial Primitive Neuroectodermal Tumor, Ewing Sarcoma of Bone, Extraosseous Ewing Sarcoma, Extraosseous Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Peripheral Primitive Neuroectodermal Tumor of the Kidney, Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
    Bendamustine and Rituximab Followed by 90-yttrium (Y) Ibritumomab Tiuxetan for Untreated Follicular Lymphoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Lymphoma, Follicular
    Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)
    Durham VA Medical Center, Durham, NC
    Durham, North Carolina 27705
    Colorectal Cancer
    The Adv Halt Trial
    Duke University Medical Center
    Durham, North Carolina 27710
    Adenovirus Disease
    Study of Lenalidomide in Combination With RICE With Lenalidomide Maintenance Post-Auto Transplant for DLBCL
    Duke University Medical Center
    Durham, North Carolina 27710
    Diffuse Large B-cell Lymphoma.
    Studying First Line Treatment of Chronic Myeloid Leukemia (CML) in a Real-world Setting
    Duke University Medical Center
    Durham, North Carolina 27710
    Chronic Myeloid Leukemia
    Pazopanib Hydrochloride in Treating Patients With Recurrent or Persistent Uterine Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Recurrent Uterine Sarcoma, Uterine Carcinosarcoma
    Single-Arm Open-Label Multicenter Study of VB-111 in Patients With Recurrent Glioblastoma Multiforme
    Duke University Medical Center
    Durham, North Carolina 27710
    Relapsed Glioblastoma Multiforme
    Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer
    Duke Cancer Institute
    Durham, North Carolina 27710
    Dysphagia, Lung Cancer, Pain, Esophagitis
    Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Small Cell Lung Cancer
    Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III or Stage IV Melanoma That Has Been Removed by Surgery
    Duke University Medical Center
    Durham, North Carolina 27710
    Recurrent Melanoma, Stage IIIB Melanoma, Stage IIIC Melanoma, Stage IV Melanoma
    Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Estrogen Receptor-negative Breast Cancer, Estrogen Receptor-positive Breast Cancer, HER2-positive Breast Cancer, Progesterone Receptor-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer, Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIC Breast Cancer
    Prevention Strategy for Pre-Menopausal Women at High Risk for Development of Breast Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Breast Cancer
    A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST
    Duke University Medical Center
    Durham, North Carolina 27710
    Gastrointestinal Stromal Tumor (GIST)
    Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)
    Duke University Medical Center
    Durham, North Carolina 27710
    GVHD, Adult Acute Myeloid Leukemia, Adult Acute Lymphoid Leukemia, Myelodysplastic Syndrome
    Safety and Efficacy of BKM120 in Patients With Metastatic Non-small Cell Lung Cancer
    Duke University Medical Center Duke 2
    Durham, North Carolina 27710
    Non-small Cell Lung Cancer
    Study of BKM120 or BEZ235 and Capecitabine in Patients With Metastatic Breast Cancer
    Duke Comprehensive Cancer Center
    Durham, North Carolina 27710
    Metastatic Breast Cancer
    Study of BHQ880 in Patients With High Risk Smoldering Multiple Myeloma
    Duke University Medical Center Duke SC
    Durham, North Carolina 27710
    Smoldering Multiple Myeloma
    A Study of Oral Sapacitabine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia
    Duke University Medical Center
    Durham, North Carolina 27710
    Acute Myeloid Leukemia
    Low-Dose Naltrexone for Glioma Patients
    Duke University Medical Center
    Durham, North Carolina 27710
    Malignant Glioma
    Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHN
    Duke University Medical Center
    Durham, North Carolina 27710
    Squamous Cell Carcinoma of the Head and Neck
    A Registry of Sipuleucel-T Therapy in Men With Advanced Prostate Cancer
    Regional Cancer Care, P.A.

    Trial Locations
    Regional Cancer Care, P.A.
    Duke University Medical Center - Duke South Clinics
    Advanced Prostate Cancer, Prostatic Neoplasms
    Afatinib (BIBW2992) in HER2-overexpressing Inflammatory Breast Cancer
    1200.89.10005 Boehringer Ingelheim Investigational Site
    Durham, North Carolina
    Breast Neoplasms
    Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor (PNET)
    Duke University Medical Center
    Durham, North Carolina 27710
    Medulloblastoma, Neuroectodermal Tumors
    Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Recurrent Neuroblastoma
    Efficacy Study of Pharmacokinetic(PK)/Pharmacodynamic(PD) Relationship of Monotherapy MORAb-004 in Metastatic Melanoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Metastatic Melanoma
    Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Hepatosplenic T-cell Lymphoma, Peripheral T-cell Lymphoma
    Exercise and Metformin in Colorectal and Breast Cancer Survivors
    Duke University
    Durham, North Carolina 27710
    Colorectal Cancer, Breast Cancer
    A Phase 1 Study of LY2787106 in Cancer and Anemia
    For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    Durham, North Carolina
    Anemia
    Patients Treated for SCID (1968-2010)
    Duke University
    Durham, North Carolina 27710
    SCID, ADA-SCID, XSCID, Leaky SCID, Omenn Syndrome, Reticular Dysgenesis
    Atorvastatin on Biomarkers of Inflammation, Coagulopathy, Angiogenesis & T-cells
    Duke Univ. Med. Ctr. Adult CRS (1601)
    Durham, North Carolina 27710
    HIV-1 Infection
    A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
    Duke University Medical Center (Peds)

    Trial Locations
    Duke University Medical Center (Peds)
    Duke Universoty Medical Center (adults)
    Hematological Malignancies, Certain Lysosomal Storage and Peroxisomal Enzyme Deficiency Disorders, Hurler Syndrome (MPS I), Krabbe Disease (Globoid Leukodystrophy), X-linked Adrenoleukodystrophy, Primary Immunodeficiency Diseases, Bone Marrow Failure, Beta-thalassemia
    Phase I Biomarker Study (BMS-936558)
    Duke University Medical Center
    Durham, North Carolina 27710
    Renal Cell Carcinoma
    Neoadjuvant Pazopanib in Renal Cell Carcinoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Renal Cell Carcinoma
    Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer
    Duke Cancer Institute
    Durham, North Carolina 27710
    Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
    Evaluation of Carboplatin/Paclitaxel With and Without Trastuzumab (Herceptin) in Uterine Serous Cancer
    Duke University School of Medicine
    Durham, North Carolina 27710
    Endometrial Cancer
    Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
    Duke Cancer Institute
    Durham, North Carolina 27710
    Prostate Cancer
    Bortezomib and Sorafenib Tosylate in Patients With Newly Diagnosed Acute Myeloid Leukemia With or Without Mutations
    Duke University Medical Center
    Durham, North Carolina 27710
    Adult Acute Erythroid Leukemia (M6), Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Pure Erythroid Leukemia (M6b), Childhood Acute Erythroleukemia (M6), Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Minimally Differentiated Myeloid Leukemia (M0), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloblastic Leukemia With Maturation (M2), Childhood Acute Myeloblastic Leukemia Without Maturation (M1), Childhood Acute Myelomonocytic Leukemia (M4), Untreated Adult Acute Myeloid Leukemia, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
    A Novel Optical Spectral Imaging System for Imaging Breast Tumor Margins
    Duke University Medical Center
    Durham, North Carolina 27710
    Breast Cancer