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A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women With Node- Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer

Phase 3
18 Years
Open (Enrolling)
Estrogen Receptor-negative Breast Cancer, Estrogen Receptor-positive Breast Cancer, HER2-positive Breast Cancer, Progesterone Receptor-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer, Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIC Breast Cancer

Thank you

Trial Information

A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women With Node- Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer


I. To determine whether the addition of trastuzumab to chemotherapy (TC or AC→WP) improves
invasive disease-free survival (IDFS) in women with resected node-positive or high-risk
node-negative breast cancer which is reported as human epidermal growth factor receptor
(HER)2-low by all HER2 testing performed.


I. To determine whether the addition of trastuzumab to chemotherapy (TC or AC→WP) improves
disease-free survival (DFS)-ductal carcinoma in situ (DCIS) of women with resected
node-positive or high-risk node-negative breast cancer which is reported as HER2-low by all
HER2 testing performed.

II. To determine whether the addition of trastuzumab to chemotherapy (TC or AC→WP) improves
breast cancer-free survival (BCFS) in women with resected node-positive or high-risk
node-negative breast cancer which is reported as HER2-low by all HER2 testing performed.

III. To determine whether the addition of trastuzumab to chemotherapy (TC or AC→WP) improves
recurrence-free interval (RFI) in women with resected node-positive or high-risk
node-negative breast cancer which is reported as HER2-low by all HER2 testing performed.

IV. To determine whether the addition of trastuzumab to chemotherapy (TC or AC→WP) improves
distant RFI in women with resected node-positive or high-risk node-negative breast cancer
which is reported as HER2-low by all HER2 testing performed.

V. To determine whether the addition of trastuzumab to chemotherapy (TC or AC→WP) improves
overall survival (OS) in women with resected node-positive or high-risk node-negative breast
cancer which is reported as HER2-low by all HER2 testing performed.

VI. To evaluate the associations between amenorrhea and circulating reproductive hormone
levels, and the associations between chemotherapy regimen, amenorrhea, and IDFS benefit in
premenopausal women eligible at baseline for the menstrual history assessments.

VII. To evaluate the toxicity associated with each of the regimens. VIII. To test the
hypothesis that the HER2 mRNA level is the predictor of the degree of benefit from
trastuzumab and the threshold for benefit in the adjuvant setting is lower than defined by
current ASCO/CAP Guidelines for HER2 assays (immunohistochemistry [IHC] and fluorescent in
situ hybridization [FISH]).

IX. To identify and/or validate molecular predictors of the degree of benefit from the
addition of trastuzumab to chemotherapy (TC or AC→WP).

X. To test the alternative hypothesis that the main determinant of trastuzumab response in
the adjuvant setting of HER2-low breast cancer is through antibody-dependent cellular
cytotoxicity (ADCC) by demonstrating that the polymorphism of the Fcγ receptor gene is
predictive of the degree of benefit from the addition of trastuzumab to chemotherapy (TC or

XI. To examine the relationship between behavioral host factors (obesity, tobacco, alcohol)
and comorbid conditions that may influence systemic inflammation and breast cancer outcomes,
controlling for tumor/stage characteristics and treatment assignment.

XII. To examine the relationship between medication exposures that may influence systemic
inflammation and breast cancer outcomes, controlling for tumor/stage characteristics and
treatment assignment.

XIII. To examine the relationship between comorbid conditions, medication exposures, and
behavioral host factors together and breast cancer outcomes, controlling for tumor/stage
characteristics and treatment assignment.

OUTLINE: This is a multicenter study. Patients are stratified according to IHC score (1+ vs
2+), number of positive nodes (0-3 vs 4-9 vs 10+), hormone receptor status (estrogen
[ER]-positive and/or progesterone receptor [PgR]-positive vs ER- and PgR-negative), and
intended chemotherapy regimen* (docetaxel and cyclophosphamide vs doxorubicin hydrochloride
and cyclophosphamide followed by paclitaxel). Patients are randomized to 1 of 2 treatment

NOTE: *Chemotherapy regimen is based on the investigator's preference.


GROUP A: Patients receive docetaxel intravenously (IV) over 60 minutes and cyclophosphamide
IV over 30 minutes on day 1. Treatment repeats every 3 weeks for 6 courses.

GROUP B: Patients receive doxorubicin hydrochloride IV over 15 minutes and cyclophosphamide
IV over 30 minutes on day 1.

Treatment repeats every 2 or 3 weeks (at the investigator's discretion) for 4 courses.
Patients then receive paclitaxel IV over 60 minutes once weekly for 12 doses.


GROUP A: Patients receive chemotherapy as in arm IA. Patients also receive trastuzumab IV
over 30-90 minutes on day 1. Trastuzumab treatment repeats every 3 weeks for 11 courses.

GROUP B: Patients receive chemotherapy as in arm IB. Patients also receive trastuzumab IV
over 30-90 minutes weekly for 12 doses. After completion of paclitaxel, patients receive
trastuzumab IV over 30-90 minutes on day 1.

Treatment repeats every 3 weeks for 13 courses. Tumor and blood samples may be collected
periodically during study treatment for correlative studies.

After completion of study treatment, patients are followed up every 6 months for 5 years and
then every 12 months for 5 years.

Inclusion Criteria:

- The tumor must be unilateral invasive adenocarcinoma of the breast on histologic

- All of the following staging criteria (according to the 7th edition of the American
Joint Committee on Cancer [AJCC] Cancer Staging Manual) must be met:

- By pathologic evaluation, primary tumor must be pT1-3

- By pathologic evaluation, ipsilateral nodes must be pN0, pN1 (pN1mi, pN1a,
pN1b,pN1c), pN2a, pN2b, pN3a, or pN3b

- If pN0, one of the following criteria must be met:

- pT2 and estrogen receptor (ER) negative and progesterone receptor
(PgR) negative

- pT2 and ER positive (PgR status may be positive or negative) and
either grade 3histology or Oncotype DX Recurrence Score of >= 25; or

- pT3 regardless of hormone receptor status, histologic grade, and
Oncotype DX Recurrence Score

- No T4 tumors including inflammatory breast cancer

- No definitive clinical or radiologic evidence of metastatic disease

- NOTE: Chest imaging (mandatory for all patients) and other imaging (if required)
must have been performed within 90 days prior to randomization

- No synchronous or previous contralateral invasive breast cancer (patients with
synchronous and/or previous contralateral DCIS or lobular carcinoma in situ [LCIS]
are eligible)

- No previous ipsilateral invasive breast cancer or ipsilateral DCIS (patients with
synchronous or previous ipsilateral LCIS are eligible)

- HER2 status of the primary tumor must be evaluated prior to randomization; all
testing performed must indicate that the tumor is HER2-low as defined below

- IHC must be performed and the IHC staining results must indicate a score of 1+
(in situ hybridization [ISH] testing is not required) or 2+ (ISH must also be
performed and must indicate that the tumor is HER2-low as described below)

- If ISH testing is performed, test results must be as follows and IHC must be 1+
or 2+: The ratio of HER2 to CEP17 must be < 2.0 or, if a ratio was not
performed, the HER2 gene copy number must be < 4 per nucleus

- Note: If the IHC staining intensity is reported as a range, e.g., 0 to 1+ or 1+
to 2+, the higher intensity score in the range should be used to determine

- No primary tumor with any of the following HER2 testing results:

- IHC staining intensity:

- 0 on all evaluations of specimens

- 3+ on evaluation of any specimen

- ISH with a ratio of HER2 to CEP17 >= 2.0 on evaluation of any specimen

- ISH result indicating HER2 gene copy number >= 4 per nucleus on evaluation of
any specimen

- The patient must have undergone either a total mastectomy or breast-conserving
surgery (lumpectomy) (patients who have had a nipple-sparing mastectomy are eligible)

- For patients who undergo lumpectomy, the margins of the resected specimen must
be histologically free of invasive tumor and DCIS as determined by the local
pathologist; if pathologic examination demonstrates tumor at the line of
resection, additional operative procedures may be performed to obtain clear
margins; if tumor is still present at the resected margin after re-excision(s),
the patient must undergo total mastectomy to be eligible (patients with margins
positive for LCIS are eligible without additional resection)

- For patients who undergo mastectomy, margins must be free of gross residual
tumor(patients with microscopic positive margins are eligible as long as
post-mastectomy RT of the chest wall will be administered)

- The interval between the last surgery for breast cancer (treatment or staging)
and randomization must be no more than 84 days

- The patient must have completed one of the procedures for evaluation of pathologic
nodal status listed below:

- Sentinel lymphadenectomy alone:

- If pathologic nodal staging based on sentinel lymphadenectomy is pN0 or

- If pathologic nodal staging based on sentinel lymphadenectomy is pN1mi or
pN1a, the primary tumor must be T1 or T2 by pathologic evaluation and the
nodal involvement must be limited to 1 or 2 positive nodes

- Sentinel lymphadenectomy followed by removal of additional non-sentinel lymph
nodes if the sentinel node (SN) is positive

- Axillary lymphadenectomy with or without SN isolation procedures

- The patient must have ER analysis performed on the primary tumor prior to
randomization; if ER analysis is negative, then PgR analysis must also be performed
(either the core biopsy or surgical resection specimen can be used for ER/PgR
testing); patients with a primary tumor that is hormone receptor-positive or
receptor-negative are eligible

- Pre- or postmenopausal

- Eastern Cooperation Oncology Group (ECOG) performance status of 0 or 1

- Absolute neutrophil count (ANC) must be >= 1,200/mm^3

- Platelet count must be >= 100,000/mm^3

- Hemoglobin must be >= 10 g/dL

- Total bilirubin must be =< upper limit of normal (ULN) for the lab unless the patient
has a bilirubin elevation > ULN to 1.5 x ULN due to Gilbert disease or similar
syndrome involving slow conjugation of bilirubin

- Alkaline phosphatase must be =< 2.5 x ULN for the lab

- Aspartate aminotransferase (AST) must be =< 1.5 x ULN for the lab (if alanine
aminotransferase [ALT] is performed instead of AST [per institution's standard
practice], the ALT value must be =< 1.5 x ULN; if both were performed, the AST must
be =< 1.5 x ULN)

- Alkaline phosphatase and AST may not both be > the ULN

- Patients with AST or alkaline phosphatase > ULN are eligible for inclusion in the
study if liver imaging (CT, MRI, PET-CT, or PET scan) performed within 90 days prior
to randomization does not demonstrate metastatic disease and the above requirements
are met

- Patients with alkaline phosphatase that is > ULN but =< 2.5 x ULN or unexplained bone
pain are eligible for inclusion in the study if a bone scan, positron emission
tomography (PET)-computed tomography (CT) scan, or PET scan performed within 90 days
prior to randomization does not demonstrate metastatic disease

- The most recent post operative serum creatinine performed within 6 weeks prior to
randomization must be =< ULN for the lab

- Not pregnant or nursing

- Negative pregnancy test

- Left ventricular ejection fraction (LVEF) assessment must be performed within 90 days
prior to randomization; LVEF assessment performed by 2-dimensional (D) echo
cardiogram is preferred, however, multi-gated acquisition (MUGA) scan maybe
substituted based on institutional preferences

- For patients who will receive the TC chemotherapy regimen, the LVEF must be >=
50% regardless of the cardiac-imaging facility's lower limit of normal

- For patients who will receive the AC→WP chemotherapy regimen, the LVEF must be
>= 55% regardless of the cardiac-imaging facility's lower limit of normal

- NOTE: Since the pre-entry LVEF serves as the baseline for comparing subsequent
LVEF assessments, it is critical that this baseline study be an accurate
assessment. If the baseline LVEF is > 70%, the investigator is encouraged to
have the accuracy of the initial LVEF result confirmed and repeat the test if
the accuracy is uncertain

- No history of non-breast malignancies (except for in situ cancers treated only by
local excision and basal cell and squamous cell carcinomas of the skin) within 5
years prior to randomization

- No cardiac disease (history of and/or active disease) that would preclude the use of
the drugs included in the treatment regimens, including, but not limited to:

- Active cardiac disease:

- Angina pectoris that requires the current use of anti-anginal medication

- Ventricular arrhythmias except for benign premature ventricular

- Supraventricular and nodal arrhythmias requiring a pacemaker or not
controlled with medication

- Conduction abnormality requiring a pacemaker

- Valvular disease with documented compromise in cardiac function

- Symptomatic pericarditis

- History of cardiac disease:

- Myocardial infarction documented by elevated cardiac enzymes or persistent
regional wall abnormalities on assessment of left ventricle (LV) function

- History of documented congestive heart failure (CHF)

- Documented cardiomyopathy

- No hypertension defined according to the following ineligibility criteria:

- For patients who will receive TC (regardless of the patient's age): uncontrolled
hypertension defined as sustained systolic blood pressure (BP) > 150 mm Hg or
diastolic BP > 90 mm Hg (patients with initial BP elevations are eligible if
initiation or adjustment of BP medication lowers pressure to meet entry

- For patients < 50 years old who will receive AC→WP: uncontrolled hypertension
defined as sustained systolic BP > 150 mm Hg or diastolic BP > 90 mm Hg
(patients with initial BP elevations are eligible if initiation or adjustment of
BP medication lowers pressure to meet entry criteria)

- For patients >= 50 years old who will receive AC→WP: uncontrolled hypertension
defined as sustained systolic BP > 150 mm Hg or diastolic BP > 90 mm Hg OR
controlled hypertension (systolic BP =< 150 mm Hg and diastolic BP =< 90 mmHg),
if anti-hypertensive medication(s) are needed

- NOTE: Patients who are not eligible based on the AC→WP regimen BP criteria but
who meet the TC regimen BP criteria are eligible for B-47 if the intended
chemotherapy regimen is changed to TC

- No active hepatitis B or hepatitis C with abnormal liver function tests

- No intrinsic lung disease resulting in dyspnea

- No poorly controlled diabetes mellitus

- No active infection or chronic infection requiring chronic suppressive antibiotics

- No nervous system disorder (paresthesia, peripheral motor neuropathy, or peripheral
sensory neuropathy) >= grade 2, per the Common Terminology Criteria for Adverse
Events (CTCAE) v4.0

- No conditions that would prohibit administration of corticosteroids

- No known hypersensitivity to any of the study drugs or excipients, e.g., polysorbate
80 and Cremophor EL

- No other non-malignant systemic disease that would preclude the patient from
receiving study treatment or would prevent required follow-up

- No psychiatric or addictive disorders or other conditions that, in the opinion of the
investigator, would preclude the patient from meeting the study requirements

- Concurrent participation in NSABP-B-39 allowed

- No previous therapy with anthracyclines, taxanes, or trastuzumab for any malignancy

- No chemotherapy or HER2-targeted therapy administered for the currently diagnosed
breast cancer prior to randomization

- No whole-breast radiation therapy (RT) prior to randomization or partial-breast RT
that cannot be completed on or before the date of randomization

- No use of any investigational product within 30 days prior to randomization

- No continued endocrine therapy such as raloxifene or tamoxifen (or other SERM) or an
aromatase inhibitor (patients are eligible if these medications are discontinued
prior to randomization)

- No continued use of sex hormonal therapy, e.g., birth control pills, ovarian hormone
replacement therapy (patients are eligible if these medications are discontinued
prior to randomization)

- No chronic daily treatment with corticosteroids with a dose of >= 10 mg/day
methylprednisol one equivalent (excluding inhaled steroids)

- No other concurrent chemotherapy

- No other concurrent targeted therapy for malignancy

- No partial-breast irradiation following randomization

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Invasive disease-free survival

Outcome Time Frame:

Time to local, regional, or distant recurrence, second non-breast primary breast cancer, or death from any cause, assessed up to 10 years

Safety Issue:


Principal Investigator

Louis Fehrenbacher

Investigator Role:

Principal Investigator

Investigator Affiliation:

National Surgical Adjuvant Breast and Bowel Project (NSABP)


United States: Food and Drug Administration

Study ID:




Start Date:

January 2011

Completion Date:

Related Keywords:

  • Estrogen Receptor-negative Breast Cancer
  • Estrogen Receptor-positive Breast Cancer
  • HER2-positive Breast Cancer
  • Progesterone Receptor-negative Breast Cancer
  • Progesterone Receptor-positive Breast Cancer
  • Recurrent Breast Cancer
  • Stage IA Breast Cancer
  • Stage IB Breast Cancer
  • Stage II Breast Cancer
  • Stage IIIA Breast Cancer
  • Stage IIIC Breast Cancer
  • Breast Neoplasms



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Fisher-Titus Medical CenterNorwalk, Ohio  44857
Clinton Memorial HospitalWilmington, Ohio  45177
Providence Centralia HospitalCentralia, Washington  98531-9027
Wenatchee Valley Medical CenterWenatchee, Washington  98801-2028
Marshfield Clinic Cancer Care at Regional Cancer CenterEau Claire, Wisconsin  54701
UW Cancer Center Johnson CreekJohnson Creek, Wisconsin  53038
Saint Joseph's HospitalMarshfield, Wisconsin  54449
Marshfield Clinic - Weston CenterWeston, Wisconsin  54476
Diagnostic and Treatment CenterWeston, Wisconsin  54476
Marshfield Clinic - Wisconsin Rapids CenterWisconsin Rapids, Wisconsin  54494
Rocky Mountain OncologyCasper, Wyoming  82609
Longmont United HospitalLongmont, Colorado  80501
Temple University HospitalPhiladelphia, Pennsylvania  19140
Genesys Regional Medical CenterGrand Blanc, Michigan  48439-8066
Singing River HospitalPascagoula, Mississippi  39581
Methodist HospitalHouston, Texas  77030
Greene Memorial HospitalXenia, Ohio  45385
Easton HospitalEaston, Pennsylvania  18042
Greater Baltimore Medical CenterBaltimore, Maryland  21204
Lowell General HospitalLowell, Massachusetts  01854
Rutherford HospitalRutherfordton, North Carolina  28139
Three Rivers Community HospitalGrants Pass, Oregon  97527
Providence Medford Medical CenterMedford, Oregon  97504
AnMed Health Cancer CenterAnderson, South Carolina  29621
Harold Alfond Center for Cancer CareAugusta, Maine  04330
Union Hospital of Cecil CountyElkton MD, Maryland  21921
Miriam HospitalProvidence, Rhode Island  02906
Cancer Centers of the Carolinas - Grove CommonsGreenville, South Carolina  29605
Cancer Centers of the Carolinas - SenecaSeneca, South Carolina  29672
Cancer Centers of the Carolinas - SpartanburgSpartanburg, South Carolina  29307
Presbyterian HospitalCharlotte, North Carolina  28233-3549
Sutter Roseville Medical CenterRoseville, California  95661
Manchester Memorial HospitalManchester, Connecticut  06040-4188
Midstate Medical CenterMeriden, Connecticut  06451
Washington Hospital CenterWashington, District of Columbia  20010
Sherman HospitalElgin, Illinois  60120-2198
Memorial Medical CenterSpringfield, Illinois  62781
Saint Anne's HospitalFall River, Massachusetts  02721
Lapeer Regional HospitalLapeer, Michigan  48446
Phelps County Regional Medical CenterRolla, Missouri  65401
Doylestown HospitalDoylestown, Pennsylvania  18901
Mercy Hospital of PhiladelphiaPhiladelphia, Pennsylvania  19143
Wellmont Holston Valley Hospital and Medical CenterKingsport, Tennessee  37662
Metro Health HospitalGrand Rapids, Michigan  49506
Queen's Medical CenterHonolulu, Hawaii  96813
University of PittsburghPittsburgh, Pennsylvania  15261
Tyler Cancer CenterTyler, Texas  75702
Cancer Care NorthwestSpokane, Washington  99202
Providence HospitalMobile, Alabama  36608
University of North CarolinaChapel Hill, North Carolina  27599
Duke University Medical CenterDurham, North Carolina  27710
Meharry Medical CollegeNashville, Tennessee  37208-3599
Lynchburg Hematology-Oncology ClinicLynchburg, Virginia  24501
East Bay Radiation Oncology CenterCastro Valley, California  94546
Contra Costa Regional Medical CenterMartinez, California  94553-3156
Larry G Strieff MD Medical CorporationOakland, California  94609
Kapiolani Medical Center at Pali MomiAiea, Hawaii  96701
Kapiolani Medical Center for Women and ChildrenHonolulu, Hawaii  96826
Elmhurst Memorial HospitalElmhurst, Illinois  60126
Hennepin County Medical CenterMinneapolis, Minnesota  
Queens Hospital CenterJamaica, New York  11432
University of FloridaGainesville, Florida  32610-0277
University of RochesterRochester, New York  14642
Cascade Cancer CenterKirkland, Washington  98034-3013
Glens Falls HospitalGlens Falls, New York  12801
Saint Alphonsus Regional Medical CenterBoise, Idaho  83706
Holy Cross HospitalFort Lauderdale, Florida  33308
El Camino HospitalMountain View, California  94040
Case Western Reserve UniversityCleveland, Ohio  44106
Yale UniversityNew Haven, Connecticut  06520
Emory UniversityAtlanta, Georgia  30322
Wayne State UniversityDetroit, Michigan  48202
Kaiser Permanente Medical CenterVallejo, California  94589
Ohio State University Medical CenterColumbus, Ohio  43210
New Hampshire Oncology-Hematology PAHooksett, New Hampshire  03106
Albert Einstein Medical CenterPhiladelphia, Pennsylvania  19141
Straub Clinic and HospitalHonolulu, Hawaii  96813
Lakeland Regional Cancer CenterLakeland, Florida  33805
Riverside Methodist HospitalColumbus, Ohio  43214
Licking Memorial HospitalNewark, Ohio  43055-2899
Cancer Center of Kansas - McPhersonMcPherson, Kansas  67460
California Pacific Medical CenterSan Francisco, California  94115
Dartmouth Hitchcock Medical CenterLebanon, New Hampshire  03756
Mid Dakota ClinicBismarck, North Dakota  58501
Columbus CCOPColumbus, Ohio  43206
Weiss Memorial HospitalChicago,, Illinois  60640
University Of VermontBurlington,, Vermont  05403
Presbyterian - Saint Lukes Medical Center - Health OneDenver, Colorado  80218
Kaiser PermanenteSacramento, California  
University of Texas Southwestern Medical CenterDallas, Texas  
University of KentuckyLexington, Kentucky  40536-0098
Wichita CCOPWichita, Kansas  67214-3882
Montana Cancer Consortium CCOPBillings, Montana  59101
Alegent Health Immanuel Medical CenterOmaha, Nebraska  68122
Alegent Health Bergan Mercy Medical CenterOmaha, Nebraska  68124
Flower HospitalSylvania, Ohio  43560-2197
Virginia Mason CCOPSeattle, Washington  98101
Mount Sinai Hospital Medical CenterChicago, Illinois  60608
Addison Gilbert HospitalGloucester, Massachusetts  01930
Southeastern Regional Medical CenterLumberton, North Carolina  28359
Granville Medical CenterOxford, North Carolina  27565
Person Memorial HospitalRoxboro, North Carolina  27573
Columbia Saint Mary's Hospital - OzaukeeMequon, Wisconsin  53097
Metro-Minnesota CCOPSt. Louis Park, Minnesota  
University of New MexicoAlbuquerque, New Mexico  87131
North Texas Regional Cancer CenterPlano, Texas  75075
Providence HospitalSouthfield, Michigan  48075
Tufts Medical CenterBoston, Massachusetts  02111
Lakeview HospitalStillwater, Minnesota  55082
Thomas Jefferson University HospitalPhiladelphia, Pennsylvania  19131
Jersey Shore Medical CenterNeptune, New Jersey  07754
Decatur Memorial HospitalDecatur, Illinois  62526
Tulane University Health Sciences CenterNew Orleans, Louisiana  70112
Mercy Medical CenterBaltimore, Maryland  21202
Louisiana State University Health Science CenterNew Orleans, Louisiana  70112
Virginia Commonwealth UniversityRichmond, Virginia  
Kaiser PermanentePortland, Oregon  97227
Frederick Memorial HospitalFrederick, Maryland  21701
Lankenau HospitalWynnewood, Pennsylvania  19096
Princeton Community HospitalPrinceton, West Virginia  24740
Holy Cross HospitalSilver Spring, Maryland  20910
Montana Cancer SpecialistsMissoula, Montana  59807-7877
Desert Regional Medical CenterPalm Springs, California  92262
Providence Saint Joseph Medical CenterBurbank, California  91505-4866
Florida HospitalOrlando, Florida  32803
Memorial Health University Medical CenterSavannah, Georgia  31404
Phoenixville HospitalPhoenixville, Pennsylvania  19460
DeKalb Medical CenterDecatur, Georgia  30033
Northern Indiana Cancer Research ConsortiumSouth Bend, Indiana  
Rockwood ClinicSpokane, Washington  99220
Rohnert Park Cancer CenterRohnert Park, California  94928
South Sacramento Cancer CenterSacramento, California  95823
University of CincinnatiCincinnati, Ohio  45267-0502
Hawaii Medical Center EastHonolulu, Hawaii  96817
Vince Lombardi Cancer Clinic - OshkoshOshkosh, Wisconsin  54904
Penn State Milton S Hershey Medical CenterHershey, Pennsylvania  17033
Hematology Oncology AssociatesAlbuquerque, New Mexico  87106
Piedmont Fayette HospitalFayetteville, Georgia  30214
Southeast Cancer CenterCape Girardeau, Missouri  63703
Butler Memorial HospitalButler, Pennsylvania  16001
The Community HospitalMunster, Indiana  46321
Littleton Adventist HospitalLittleton, Colorado  80122
Parker Adventist HospitalParker, Colorado  80138
New Ulm Medical CenterNew Ulm, Minnesota  56073
United Hospital CenterClarksburg, West Virginia  26301
Upper Chesapeake Medical CenterBel Air, Maryland  21014
OSF Saint Francis Medical CenterPeoria, Illinois  61637
Northside HospitalAtlanta, Georgia  30342
Saint Helena HospitalSaint Helena, California  94574
Mills - Peninsula HospitalsBurlingame, California  94010
Valley Medical Oncology Consultants-Castro ValleyCastro Valley, California  94546
Northbay Cancer CenterFairfield, California  94533
Valley Medical Oncology Consultants-FremontFremont, California  94538
Kaiser Permanente, FremontFremont, California  94538
Kaiser Permanente, HaywardHayward, California  94545
Community Hospital of Monterey PeninsulaMonterey, California  93940
Palo Alto Medical Foundation-Camino DivisionMountain View, California  94040
Bay Area Breast Surgeons IncOakland, California  94609
Bay Area Tumor Institution CCOPOakland, California  94609
Tom K Lee IncOakland, California  94609
Kaiser Permanente-OaklandOakland, California  94611
Saint Joseph HospitalOrange, California  92868
Palo Alto Medical Foundation Heath CarePalo Alto, California  94301
Kaiser Permanente-Redwood CityRedwood City, California  94063
Kaiser Permanente-RichmondRichmond, California  94801
Kaiser Permanente-RosevilleRoseville, California  95661
Sutter General HospitalSacramento, California  95816
Kaiser Permanente-South SacramentoSacramento, California  95823
Kaiser Permanente - SacramentoSacramento, California  95825
Kaiser Permanente-San FranciscoSan Francisco, California  94115
Kaiser Permanente-Santa Teresa-San JoseSan Jose, California  95119
Doctors Medical Center- JC Robinson Regional Cancer CenterSan Pablo, California  94806
Kaiser Permanente-San RafaelSan Rafael, California  94903
Kaiser Permanente-Santa RosaSanta Rosa, California  95403
Kaiser Permanente-South San FranciscoSouth San Francisco, California  94080
Kaiser Permanente-StocktonStockton, California  95210
Kaiser Permanente-VallejoVallejo, California  94589
Kaiser Permanente-Walnut CreekWalnut Creek, California  94596
The Medical Center of AuroraAurora, Colorado  80012
Penrose-Saint Francis HealthcareColorado Springs, Colorado  80907
Memorial Hospital Colorado SpringsColorado Springs, Colorado  80909
Saint Anthony Central HospitalDenver, Colorado  80204
Exempla Saint Joseph HospitalDenver, Colorado  80218
Colorado Cancer Research Program CCOPDenver, Colorado  80224-2522
Saint Mary's Hospital and Regional Medical CenterGrand Junction, Colorado  81502
Saint Mary Corwin Medical CenterPueblo, Colorado  81004
Saint Francis Hospital and Medical CenterHartford, Connecticut  06105
The Hospital of Central ConnecticutNew Britain, Connecticut  06050
Bayhealth Medical Center at Kent GeneralDover, Delaware  19901
Lombardi Comprehensive Cancer Center at Georgetown UniversityWashington, District of Columbia  20057
Edna Williams Cancer Center at the Baptist Cancer InstituteJacksonville, Florida  32207
The Watson ClinicLakeland, Florida  33805
M D Anderson Cancer Center- OrlandoOrlando, Florida  32806
Phoebe Putney Memorial HospitalAlbany, Georgia  31703
Atlanta Regional CCOPAtlanta, Georgia  30342
Well Star Cobb HospitalAustell, Georgia  30106
John B Amos Cancer CenterColumbus, Georgia  31904
Wellstar Kennestone HospitalMarietta, Georgia  30060
Saint Joseph's-Candler Health SystemSavannah, Georgia  31405
Oncare Hawaii Inc-POB IIHonolulu, Hawaii  96813
Oncare Hawaii Inc-KuakiniHonolulu, Hawaii  96817
University of HawaiiHonolulu, Hawaii  96813
Saint Luke's Mountain States Tumor InstituteBoise, Idaho  83712
Saint Anthony's HealthAlton, Illinois  62002
Rush - Copley Medical CenterAurora, Illinois  60504
John H Stroger Jr Hospital of Cook CountyChicago, Illinois  60612-3785
Resurrection HealthcareChicago, Illinois  60631
Cancer Institute at Alexian BrothersElk Grove Village, Illinois  60007
Saint Francis HospitalEvanston, Illinois  60202
Joliet Oncology-Hematology Associates LimitedJoliet, Illinois  60435
Provena Saint Mary's HospitalKankakee, Illinois  60901
Good Samaritan Regional Medical CenterMt. Vernon, Illinois  62864
Community Cancer Center FoundationNormal, Illinois  61761
Illinois CancerCare-Ottawa ClinicOttawa, Illinois  61350
Ottawa Regional Hospital and Healthcare CenterOttawa, Illinois  61350
Pekin Cancer Treatment CenterPekin, Illinois  61554
Illinois Oncology Research Association CCOPPeoria, Illinois  61615
Illinois CancerCare-PeoriaPeoria, Illinois  61615
Illinois Valley HospitalPeru, Illinois  61354
West Suburban Cancer CenterRiver Forest, Illinois  60305
Saint Francis Hospital and Health CentersBeech Grove, Indiana  46107
Fort Wayne Medical Oncology and Hematology Inc - State BoulevardFort Wayne, Indiana  46845
Saint Vincent Hospital and Health ServicesIndianapolis, Indiana  46260
Saint Anthony Memorial Health CenterMichigan City, Indiana  46360
Reid Hospital and Health Care ServicesRichmond, Indiana  47374
McFarland ClinicAmes, Iowa  50010
Cedar Rapids Oncology AssociationCedar Rapids, Iowa  52403
Iowa Blood and Cancer Care PLCCedar Rapids, Iowa  52402
Mercy HospitalCedar Rapids, Iowa  52403
Saint Luke's HospitalCedar Rapids, Iowa  52402
Medical Oncology and Hematology Associates-West Des MoinesClive, Iowa  50325
Genesis Medical Center - East CampusDavenport, Iowa  52803
Iowa Oncology Research Association CCOPDes Moines, Iowa  50309
Mercy Medical Center - Des MoinesDes Moines, Iowa  50314
Medical Oncology and Hematology Associates-Des MoinesDes Moines, Iowa  50309
Mercy Medical Center-Sioux CitySioux City, Iowa  51104
Saint Luke's Regional Medical CenterSioux City, Iowa  51104
Covenant Medical CenterWaterloo, Iowa  50702
Cancer Center of Kansas - El DoradoEl Dorado, Kansas  67042
Cancer Center of Kansas-KingmanKingman, Kansas  67068
Cancer Center of Kansas - ParsonsParsons, Kansas  67357
Cancer Center of Kansas - PrattPratt, Kansas  67124
Cancer Center of Kansas-Wichita Medical Arts TowerWichita, Kansas  67208
Cancer Center of Kansas - Main OfficeWichita, Kansas  67214
Ochsner Clinic Foundation-Baton RougeBaton Rouge, Louisiana  70809
Medical Center of LouisianaNew Orleans, Louisiana  70112
Ochsner Clinic CCOPNew Orleans, Louisiana  70121
Highland ClinicShreveport, Louisiana  71105
Washington County HospitalHagerstown, Maryland  21740
Associates In Oncology Hematology PC-RockvilleRockville, Maryland  20878
Holy Family HospitalMethuen, Massachusetts  01844
North Shore Medical Center Cancer CenterPeabody, Massachusetts  01960
Berkshire Hematology Oncology PCPittsfield, Massachusetts  01201
Commonwealth Hematology Oncology PC-QuincyQuincy, Massachusetts  02169
Hickman Cancer CenterAdrian, Michigan  49221
Michigan Cancer Research Consortium Community Clinical Oncology ProgramAnn Arbor, Michigan  48106
Oakwood HospitalDearborn, Michigan  48123
Saint John Hospital and Medical CenterDetroit, Michigan  48236
Michigan State University - Breslin Cancer CenterEast Lansing, Michigan  48824-1313
Green Bay Oncology - EscanabaEscanaba, Michigan  49431
McLaren Regional Medical CenterFlint, Michigan  48532
Grand Rapids Clinical Oncology ProgramGrand Rapids, Michigan  49503
Saint Mary's Health CareGrand Rapids, Michigan  49503
Spectrum Health at Butterworth CampusGrand Rapids, Michigan  49503
Green Bay Oncology - Iron MountainIron Mountain, Michigan  49801
Allegiance HealthJackson, Michigan  49201
Ingham Regional Medical CenterLansing, Michigan  48910
Sparrow HospitalLansing, Michigan  48912
Saint Mary Mercy HospitalLivonia, Michigan  48154
Mid-Michigan Medical Center - MidlandMidland, Michigan  48670
Mercy Memorial HospitalMonroe, Michigan  48162
Mercy Health Partners-Mercy CampusMuskegon, Michigan  49443
Northern Michigan Regional HospitalPetoskey, Michigan  49770
Saint Joseph Mercy OaklandPontiac, Michigan  48341-2985
Saint Joseph Mercy Port HuronPort Huron, Michigan  48060
Saint Mary's of MichiganSaginaw, Michigan  48601
Lakeland HospitalSt. Joseph, Michigan  49085
Saint John Macomb-Oakland HospitalWarren, Michigan  48093
Medini, Eitan MD (UIA Investigator)Alexandria, Minnesota  56308
Miller-Dwan HospitalDuluth, Minnesota  55805
Saint Luke's Hospital of DuluthDuluth, Minnesota  55805
Unity HospitalFridley, Minnesota  55432
Immanuel-Saint Joseph Hospital-Mayo Health SystemMankato, Minnesota  56002
Saint John's Hospital - HealtheastMaplewood, Minnesota  55109
Minnesota Oncology Hematology PA-MaplewoodMaplewood, Minnesota  55109
North Memorial Medical Health CenterRobbinsdale, Minnesota  55422
Saint Cloud HospitalSaint Cloud, Minnesota  56303
Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, Minnesota  55416
Minnesota Oncology and Hematology PA-WoodburyWoodbury, Minnesota  55125
Freeman Health SystemJoplin, Missouri  64804
Saint Luke's Cancer InstituteKansas City, Missouri  64111
Saint Luke's Hospital of Kansas CityKansas City, Missouri  64111
Saint Joseph Health CenterKansas City, Missouri  64114
Liberty Radiation Oncology ClinicKansas City, Missouri  64116
Saint Anthony's Medical CenterSaint Louis, Missouri  63128
Saint Louis-Cape Girardeau CCOPSaint Louis, Missouri  63141
Missouri Baptist Medical CenterSaint Louis, Missouri  63131
Saint John's Mercy Medical CenterSaint Louis, Missouri  63141
Ozark Health Ventures LLC dba Cancer Research for The Ozarks SpringfieldSpringfield, Missouri  65802
Saint John's HospitalSpringfield, Missouri  65804
Cox Medical CenterSpringfield, Missouri  65807
Hematology-Oncology Centers of the Northern Rockies PCBillings, Montana  59101
Saint Vincent HealthcareBillings, Montana  59101
Billings ClinicBillings, Montana  59107-7000
Saint James Community Hospital and Cancer Treatment CenterButte, Montana  59701
Benefis Healthcare- Sletten Cancer InstituteGreat Falls, Montana  59405
Saint Peter's Community HospitalHelena, Montana  59601
Glacier Oncology PLLCKalispell, Montana  59901
Saint Patrick Hospital - Community HospitalMissoula, Montana  59802
Good Samaritan HospitalKearney, Nebraska  68847
Lincoln Medical Education Foundation Cancer Resource CenterLincoln, Nebraska  68510
Missouri Valley Cancer Consortium CCOPOmaha, Nebraska  68106
Nevada Cancer Research Foundation CCOPLas Vegas, Nevada  89106
Exeter HospitalExeter, New Hampshire  03833
New Hampshire Oncology Hematology AssociatesHooksett, New Hampshire  03106
Cheshire Medical Center-Dartmouth-Hitchcock KeeneKeene, New Hampshire  03431
LRGHealthcare-Lakes Region General HospitalLaconia, New Hampshire  03246
Cooper Hospital University Medical CenterCamden, New Jersey  08103
Hunterdon Medical CenterFlemington, New Jersey  08822
Saint Barnabas Medical CenterLivingston, New Jersey  07039
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington CountyMount Holly, New Jersey  08060
Sparta Cancer Treatment CenterSparta, New Jersey  07871
South Jersey HealthcareVineland, New Jersey  08360
Virtua West Jersey Hospital VoorheesVoorhees, New Jersey  08043
University of New Mexico at Lovelace Medical CenterAlbuquerque, New Mexico  87102
Presbyterian Kaseman HospitalAlbuquerque, New Mexico  87110
Memorial Medical Center - Las CrucesLas Cruces, New Mexico  88011
Orange Regional Medical CenterMiddletown, New York  10940
Saint Luke's Roosevelt Hospital Center - Saint Luke's DivisionNew York, New York  10025
Columbia University Medical CenterNew York, New York  10032
Interlakes Foundation Inc-RochesterRochester, New York  14623
Highland HospitalRochester, New York  14620
State University of New York Upstate Medical UniversitySyracuse, New York  13210
Dickstein Cancer Treatment CenterWhite Plains, New York  10601
Mission Hospitals IncAsheville, North Carolina  28801
Alamance Regional Medical CenterBurlington, North Carolina  27216
Gaston Memorial HospitalGastonia, North Carolina  28054
Wayne Memorial HospitalGoldsboro, North Carolina  27534
Margaret R Pardee Memorial HospitalHendersonville, North Carolina  28791
Kinston Medical Specialists PAKinston, North Carolina  28501
Marion L Shepard Cancer CenterWashington, North Carolina  27889
Saint Alexius Medical CenterBismarck, North Dakota  58501
Summa Barberton HospitalBarberton, Ohio  44203
Aultman Health FoundationCanton, Ohio  44710
Doctors HospitalColumbus, Ohio  43228
Grant Medical CenterColumbus, Ohio  43215
Mount Carmel Health Center WestColumbus, Ohio  43222
Good Samaritan Hospital - DaytonDayton, Ohio  45406
Dayton CCOPDayton, Ohio  45429
Samaritan North Health CenterDayton, Ohio  45415
Hematology Oncology Center IncorporatedElyria, Ohio  44035
Blanchard Valley HospitalFindlay, Ohio  45840
Atrium Medical Center-Middletown Regional HospitalFranklin, Ohio  45005-1066
Kettering Medical CenterKettering, Ohio  45429
Saint Rita's Medical CenterLima, Ohio  45801
Mansfield General Hospital-MedCentral Health SystemMansfield, Ohio  44903
Marietta Memorial HospitalMarietta, Ohio  45750
Toledo Radiation Oncology at Northwest Ohio Onocolgy CenterMaumee, Ohio  43537
Saint Charles HospitalOregon, Ohio  43616
North Coast Cancer CareSandusky, Ohio  44870
Toledo Community Hospital Oncology Program CCOPToledo, Ohio  43617
Mercy Cancer Center at Saint Anne Mercy HospitalToledo, Ohio  43623
University of ToledoToledo, Ohio  43614
Saint Vincent Mercy Medical CenterToledo, Ohio  43608
Upper Valley Medical CenterTroy, Ohio  45373
Saint Ann's HospitalWesterville, Ohio  43081
Wright-Patterson Medical CenterWright-Patterson Afb, Ohio  45433-5529
Genesis HealthCare SystemZanesville, Ohio  43701
Natalie W Bryant Cancer CenterTulsa, Oklahoma  74136
Legacy Good Samaritan Hospital and Medical CenterPortland, Oregon  97210
Salem HospitalSalem, Oregon  97309
Pocono Medical CenterEast Stroudsburg, Pennsylvania  18301
Ephrata Cancer CenterEphrata, Pennsylvania  17522
Riddle HospitalMedia, Pennsylvania  19063
Pottstown Memorial Medical CenterPottstown, Pennsylvania  19464
Saint Joseph Medical CenterReading, Pennsylvania  19605
Hematology and Oncology Associates of North East PennsylvaniaScranton, Pennsylvania  18508
Scranton Hematology OncologyScranton, Pennsylvania  18510
Mercy HospitalScranton, Pennsylvania  18501
Associates In Hematology Oncology PC-UplandUpland, Pennsylvania  19013
Geisinger Wyoming ValleyWilkes-Barre, Pennsylvania  18711
Mainline Health CCOPWynnewood, Pennsylvania  19096
Kent County HospitalWarwick, Rhode Island  02886
AnMed Health HospitalAnderson, South Carolina  29621
Greenville CCOPGreenville, South Carolina  29615
Greenville Memorial HospitalGreenville, South Carolina  29605
Upstate Carolina CCOPSpartanburg, South Carolina  29303
Conklin Regional Cancer CenterAberdeen, South Dakota  57401
Sanford Cancer Center-Oncology ClinicSioux Falls, South Dakota  57104
Texas Health Presbyterian Hospital DallasDallas, Texas  75231
Fredericksburg Oncology IncFredericksburg, Virginia  22401
Peninsula Cancer Institute-Newport NewsNewport News, Virginia  23601
Southwest VA Regional Cancer CenterNorton, Virginia  24273
Harrison Bremerton Hematology and OncologyBremerton, Washington  98310
Saint Francis HospitalFederal Way, Washington  98003
Columbia Basin Hematology and Oncology PLLCKennewick, Washington  99336
Evergreen Hospital Medical CenterKirkland, Washington  98033
Providence - Saint Peter HospitalOlympia, Washington  98506-5166
Good Samaritan Community HospitalPuyallup, Washington  98372
Minor and James Medical PLLCSeattle, Washington  98104
The PolyclinicSeattle, Washington  98122
Swedish Medical Center-First HillSeattle, Washington  98122-4307
Northwest CCOPTacoma, Washington  98405
Multicare Health SystemTacoma, Washington  98415
Saint Clare HospitalTacoma, Washington  98499
Saint Joseph Medical CenterTacoma, Washington  98405
Edwards Comprehensive Cancer CenterHuntington, West Virginia  25701
West Virginia UniversityMorgantown, West Virginia  26506
Wheeling HospitalWheeling, West Virginia  26003
Langlade Hospital and Cancer CenterAntigo, Wisconsin  54409
Sacred Heart HospitalEau Claire, Wisconsin  54701
Central Wisconsin Cancer ProgramFond Du Lac, Wisconsin  54935
Saint Vincent HospitalGreen Bay, Wisconsin  54301
Green Bay Oncology Limited at Saint Mary's HospitalGreen Bay, Wisconsin  54303
Saint Mary's HospitalGreen Bay, Wisconsin  54303
Green Bay Oncology at Saint Vincent HospitalGreen Bay, Wisconsin  54301-3526
Aurora BayCare Medical CenterGreen Bay, Wisconsin  54311-6519
Dean Hematology and Oncology ClinicMadison, Wisconsin  53717
Vince Lombardi Cancer Clinic-MarinetteMarinette, Wisconsin  54143
Bay Area Medical CenterMarinette, Wisconsin  54143
Marshfield Clinic-Minocqua CenterMinocqua, Wisconsin  54548
Oconomowoc Memorial Hospital-ProHealth Care IncOconomowoc, Wisconsin  53066-3896
Green Bay Oncology - Oconto FallsOconto Falls, Wisconsin  54154
Marshfield Clinic at James Beck Cancer CenterRhinelander, Wisconsin  54501
Marshfield Clinic-Rice Lake CenterRice Lake, Wisconsin  54868
Saint Michael's HospitalStevens Point, Wisconsin  54481
Green Bay Oncology - Sturgeon BaySturgeon Bay, Wisconsin  54235
Marshfield Clinic-Wausau CenterWausau, Wisconsin  54401
Aspirus Regional Cancer CenterWausau, Wisconsin  54401
Women and Infants HospitalProvidence, Rhode Island  02905
University of Maryland Greenebaum Cancer CenterBaltimore, Maryland  21201
Jupiter Medical CenterJupiter, Florida  33458
Rutland Regional Medical CenterRutland, Vermont  05701
Puget Sound Cancer CenterEdmonds, Washington  98026
Henry Ford Macomb HospitalClinton Township, Michigan  48038
University of IllinoisChicago, Illinois  60612
Stony Brook University Medical CenterStony Brook, New York  11794
Alle-Kiski Medical CenterNatrona Heights, Pennsylvania  15065
Roger Maris Cancer CenterFargo, North Dakota  58122
Great Lakes Cancer InstituteLansing, Michigan  48910
Lahey Clinic Medical CenterBurlington, Massachusetts  01805
Baptist Hospital EastLouisville, Kentucky  40207
Elkhart ClinicElkhart, Indiana  46515
John Muir Medical Center-Concord CampusConcord, California  94520
Mount Sinai Medical Center CCOPMiami Beach, Florida  33140
Northeast Georgia Cancer Care LLCAthens, Georgia  30607
Harbin Clinic Medical Oncology and Clinical ResearchRome, Georgia  30165
Portneuf Medical CenterPocatello, Idaho  83201
Kootenai Cancer CenterPost Falls, Idaho  83854
Illinois CancerCare-BloomingtonBloomington%, Illinois  61701
Illinois CancerCare-CantonCanton, Illinois  61520
Illinois CancerCare-CarthageCarthage, Illinois  62321
Illinois CancerCare-EurekaEureka, Illinois  61530
Delnor Community HospitalGeneva, Illinois  60134
Illinois CancerCare-HavanaHavana, Illinois  62644
Illinois CancerCare-Kewanee ClinicKewanee, Illinois  61443
Illinois CancerCare-MacombMacomb, Illinois  61455
Illinois CancerCare-MonmouthMonmouth, Illinois  61462
Illinois CancerCare-Community Cancer CenterNormal, Illinois  61761
Illinois CancerCare-PekinPekin, Illinois  61603
Illinois CancerCare-PeruPeru, Illinois  61354
Illinois CancerCare-PrincetonPrinceton, Illinois  61356
Illinois CancerCare-Spring ValleySpring Valley, Illinois  61362
Michiana Hematology Oncology PC-ElkhartElkhart, Indiana  46514
Michiana Hematology Oncology PC-PlymouthPlymouth, Indiana  46563
Michiana Hematology Oncology PC-South BendSouth Bend, Indiana  46601
Michiana Hematology Oncology-PC WestvilleWestville, Indiana  46391
Cancer Center of Kansas-LiberalLiberal, Kansas  67901
Saint Agnes HospitalBaltimore, Maryland  21229
The Memorial Hospital at EastonEaston, Maryland  21601
University of Michigan University HospitalAnn Arbor, Michigan  48109
Michiana Hematology Oncology PC-NilesNiles, Michigan  49120
Central Care Cancer Center-Carrie J Babb Cancer CenterBolivar, Missouri  65613
University of Missouri - Ellis FischelColumbia, Missouri  65203
UMDNJ - New Jersey Medical SchoolNewark, New Jersey  07103
Carolinas Medical Center - NortheastConcord, North Carolina  28025
Rex Cancer CenterRaleigh, North Carolina  27607
Duke Raleigh HospitalRaleigh, North Carolina  27609
North Coast Cancer Care-ClydeClyde, Ohio  43410
Community Health Partners Regional Medical CenterElyria, Ohio  44035
Oncology Hematology Associates of Northern PennsylvaniaDubois, Pennsylvania  15801
Saint Mary Medical and Regional Cancer CenterLanghorne, Pennsylvania  19047
Roper HospitalCharleston, South Carolina  29401
Cancer Centers of the Carolinas - FarisGreenville, South Carolina  29605
Cancer Centers of the Carolinas-Greer Medical OncologyGreer, South Carolina  29650
Texas Oncology - Round Rock Cancer CenterRound Rock, Texas  78681
Sandra L Maxwell Cancer CenterCedar City, Utah  84720
Intermountain Medical CenterMurray, Utah  84157
Utah Valley Regional Medical CenterProvo, Utah  84603
Dixie Medical Center Regional Cancer CenterSaint George, Utah  84770
Utah Cancer Specialists-Salt Lake CitySalt Lake City, Utah  84106
Virginia Oncology Associates-HamptonHampton, Virginia  23666
Skagit Valley HospitalMt. Vernon, Washington  98273
Evergreen Hematology and Oncology PSSpokane, Washington  99218
West Virginia University CharlestonCharleston, West Virginia  25304
Marshfield Clinic-Chippewa CenterChippewa Falls, Wisconsin  54729
Holy Family Memorial HospitalManitowoc, Wisconsin  54221
Wheaton Franciscan Healthcare - Saint JosephMilwaukee, Wisconsin  53210
Wheaton Franciscan Cancer Care - All SaintsRacine, Wisconsin  53405
Vince Lombardi Cancer Clinic-SheboyganSheboygan, Wisconsin  53081
Marshfield Clinic Cancer Care at Saint Michael's HospitalStevens Point, Wisconsin  54481
Aurora Medical Center in SummitSummit, Wisconsin  53066
Vince Lombardi Cancer ClinicTwo Rivers, Wisconsin  54241
Riverview HospitalWisconsin Rapids, Wisconsin  54494
Texas Oncology PADallas, Texas  75231
Texas Cancer Center-ShermanSherman, Texas  75090
Premiere Oncology of ArizonaScottsdale, Arizona  85260
Advocate Lutheran General HospitalPark Ridge, Illinois  60068
Monter Cancer CenterLake Success, New York  11042
Hope, A Women's Cancer CenterAsheville, North Carolina  28816
Long Beach Memorial Medical Center-Todd Cancer InstituteLong Beach, California  90806
Kaiser Permanente Los Angeles Medical CenterLos Angeles, California  90027
Saint Vincent's Medical CenterJacksonville, Florida  32204
Grady Health SystemAtlanta, Georgia  30303
Norton Health Care Pavilion - DowntownLouisville, Kentucky  40202
Kaiser Permanente - Largo Medical CenterLargo, Maryland  20774
Kaiser Permanente - Shady Grove Medical CenterRockville, Maryland  20850
FirstHealth of the Carolinas-Moore Regional HosiptalPinehurst, North Carolina  28374
Kaiser Permanente - Fair Oaks Medical CenterFairfax, Virginia  22033
Cancer Centers of Southwest Oklahoma ResearchLawton, Oklahoma  
Western Maryland Health SystemCumberland, Maryland  21502
Saint Luke's Mountain States Tumor Institute - FruitlandFruitland, Idaho  83619
Kaiser Anaheim Medical CenterAnaheim, California  92807
Kaiser Permanente-Deer Valley Medical CenterAntioch, California  94531
Kaiser Permanente Medical Group - Baldwin ParkBaldwin Park, California  91706
Kaiser Foundation HospitalBellflower, California  90706
Kaiser Permanente HospitalFontana, California  92335
Kaiser Permanente - Harbor CityHarbor City, California  90710
Kaiser Permanente-West Los AngelesLos Angeles, California  90034
Epic Care-OaklandOakland, California  94612
Kaiser Permanente Oakland-BroadwayOakland, California  94611
Kaiser Permanente - Panorama CityPanorama City, California  91402
Palchak David MDPismo Beach, California  93449
Kaiser Permanente-Rancho Cordova Cancer CenterRancho Cardova, California  95670
The Permanente Medical Group-Roseville Radiation OncologyRoseville, California  95678
Salinas Valley MemorialSalinas, California  93901
Kaiser Permanente at San DiegoSan Diego, California  92120
Kaiser Permanente Health CareSan Marcos, California  92069
Kaiser Permanente Radiation Oncology Cancer Treatment CenterSanta Clara, California  95051
Kaiser Permanente Cancer Treatment CenterSouth San Francisco, California  94080
Kaiser Permanente Medical Center-VacavilleVacaville, California  95688
Kaiser Permanente-Rock CreekLafayette, Colorado  80026
Kaiser Permanente Moanalua Medical CenterHonolulu, Hawaii  96819
Wilcox Memorial Hospital and Kauai Medical ClinicLihue, Hawaii  96766-1099
Saint Joseph Regional Medical CenterLewiston, Idaho  83501
Saint Luke's Mountain States Tumor Institute - MeridianMeridian, Idaho  83642
Saint Luke's Mountain States Tumor Institute - NampaNampa, Idaho  83686
Central DuPage Hospital Cancer CenterWarrenville, Illinois  60555
Saint John's Health System Cancer CenterAnderson, Indiana  46016
Saint Luke's South HospitalOverland Park, Kansas  66213
Kansas City CCOPPrairie Village, Kansas  66208
Owensboro Mercy Medical CenterOwensboro, Kentucky  42303
Hematology and Oncology ClinicBaton Rouge, Louisiana  70809
Ochsner North Shore Medical CenterCovington, Louisiana  70433
Veterans Administration Medical CenterBaltimore, Maryland  21201
Singh and Arora Hematology Oncology PCFlint, Michigan  48532
Great Lakes Cancer Institute-Lapeer CampusLapeer, Michigan  48446
Mount Clemens Regional Medical CenterMount Clemens, Michigan  48043
Spectrum Health Reed City HospitalReed City, Michigan  49677
Capital Region Medical Center-Goldschmidt Cancer CenterJefferson City, Missouri  65109
Heartland Hematology and Oncology Associates IncorporatedKansas City, Missouri  64118
Saint John's Clinic-Rolla-Cancer and HematologyRolla, Missouri  65401
Saint Joseph Oncology IncSaint Joseph, Missouri  64507
Comprehensive Cancer Care PCSaint Louis, Missouri  63141
Arnot Ogden Medical CenterElmira, New York  14905
Saint FrancisPoughkeepsie, New York  12601
Forsyth Memorial HospitalWinston-Salem, North Carolina  27103
Mount Carmel East HospitalColumbus, Ohio  43213
The Mark H Zangmeister CenterColumbus, Ohio  43219
Southern Ohio Medical CenterPortsmouth, Ohio  45662
Saint Charles Medical Center-BendBend, Oregon  97701
Asante Health SystemMedford, Oregon  97504
Rogue Valley Medical CenterMedford, Oregon  97504
Mid-Columbia Medical CenterThe Dalles, Oregon  97058
Susquehanna Cancer CenterWilliamsport, Pennsylvania  17701
Saint Francis HospitalGreenville, South Carolina  29601
Carolina Cancer SpecialistsRock Hill, South Carolina  29732
Hematology Oncology Associates of Fredericksburg IncFredericksburg, Virginia  22401
Cancer Care Center at Island HospitalAnacortes, Washington  98221
Overlake Hospital Medical CenterBellevue, Washington  98004
Highline Medical Center-Main CampusBurien, Washington  98166
Providence Regional Cancer PartnershipEverett, Washington  98201
Pacific Medical Center-First HillSeattle, Washington  98104
United General HospitalSedro-Woolley, Washington  98284
Legacy Salmon Creek HospitalVancouver, Washington  98686
Saint Mary's Medical CenterHuntington, West Virginia  25702
Gundersen LutheranLa Crosse, Wisconsin  54601
Saint Nicholas HospitalMadison, Wisconsin  53715
Columbia Saint Mary's Water Tower Medical CommonsMilwaukee, Wisconsin  53211
Fairbanks Memorial HospitalFairbanks, Alaska  99701
Alegent Health Lakeside HospitalOmaha, Nebraska  68130
New York Oncology Hematology PC -Albany Medical CenterAlbany, New York  12208
New York Oncology Hematology PC - AlbanyAlbany, New York  12206
New York Oncology Hematology PC - AmsterdamAmsterdam, New York  12010
New York Oncology Hematology PC-HudsonHudson, New York  12534
New York Oncology Hematology PC - LathamLatham, New York  12110
New York Oncology Hematology PC - RexfordRexford, New York  12148
New York Oncology Hematology PC - TroyTroy, New York  12180
Community Regional Cancer Care-East Radiation OncologyIndianapolis, Indiana  46219
Community Regional Cancer Care-NorthIndianapolis, Indiana  46256
Stanford University Hospitals and ClinicsStanford, California  94305
Kaiser Permanente-FranklinDenver, Colorado  80205
Beaufort Memorial HospitalBeaufort, South Carolina  29902
Siouxland Hematology Oncology AssociatesSioux City, Iowa  51101
Walter Reed National Military Medical CenterBethesda, Maryland  20889
University Medical Center BrackenridgeAustin, Texas  78701
Skagit Valley Hospital Regional Cancer Care CenterMount Vernon, Washington  98274
Olympic Medical Cancer Care CenterSequim, Washington  98384
Rockwood Cancer Treatment CenterSpokane, Washington  99204
Providence Saint Mary Regional Cancer CenterWalla Walla, Washington  99362
Gulfport Memorial HospitalGulfport, Mississippi  39502
INTEGRIS Cancer Institute of OklahomaOklahoma City, Oklahoma  73142
Swedish Cancer Institute-IssaquahIssaquah, Washington  98029
Norris Cotton Cancer Center-ManchesterManchester, New Hampshire  03104
Dublin Hematology Oncology Care PCDublin, Georgia  31021
Overlake Internal Medicine AssociatesBellevue, Washington  98004
Saint Joseph's Regional Medical CenterPaterson, New Jersey  07503
Forbes Regional HospitalMonroeville, Pennsylvania  15146
Methodist West HospitalWest Des Moines, Iowa  50266-7700
Georgia Health Sciences UniversityAugusta, Georgia  30912
Georgetown Hospital SystemGeorgetown, South Carolina  29440
Texas Oncology PA - AmarilloAmarillo, Texas  79106
Texas Oncology - GarlandGarland, Texas  75042
Texas Oncology - LewisvilleLewisville, Texas  75067
Alta Bates Summit Medical Center-Herrick CampusBerkeley, California  94704
Carle Foundation - Carle Cancer CenterUrbana, Illinois  61801
Michiana Hematology Oncology PC-MishawakaMishawaka, Indiana  46545-1470
Oncology Associates at Mercy Medical CenterCedar Rapids, Iowa  52403
Marie Yeager Cancer CenterSaint Joseph, Michigan  49085
Hematology Oncology Associates of Central New York PCEast Syracuse, New York  13057
Mount Kisco Medical Group at Northern Westchester HospitalMount Kisco, New York  10549-3417
Sanford Clinic North-FargoFargo, North Dakota  58102
Sanford Medical Center-FargoFargo, North Dakota  58122
Texas Oncology-Wichita Falls Texoma Cancer CenterWichita Fall, Texas  76310
Emory University Hospital MidtownAtlanta, Georgia  30308
Summa Akron City HospitalAkron, Ohio  44304
Roy and Patricia Disney Family Cancer CenterBurbank, California  91505
Primary Oncology NetworkFairmont, West Virginia  26554
Franciscan St. Francis HealthIndianapolis, Indiana  46237
Texas Oncology-Denton SouthDenton, Texas  76210
The Toledo Hospital/Toledo Children's HospitalToledo, Ohio  43606
Sanford USD Medical Center - Sioux FallsSioux Falls, South Dakota  57117-5134
North Shore-LIJ Health System CCOPManhasset, New York  11030
Genesys Regional Medical Center-West Flint CampusFlint, Michigan  48532
Sanford Clinic North-BemidgiBemidji, Minnesota  56601
Essentia Health Saint Joseph's Medical CenterBrainerd, Minnesota  56401
Essentia Health Duluth Clinic CCOPDuluth, Minnesota  55805
Essentia Health Saint Mary's Medical CenterDuluth, Minnesota  55805
Sanford Bismarck Medical CenterBismarck, North Dakota  58501
Toledo Clinic Cancer Centers-OregonOregon, Ohio  43616
Geisinger Medical Center-Cancer Center HazeltonHazleton, Pennsylvania  18201
Community Howard Regional HealthKokomo, Indiana  46904
Indiana University Health La Porte HospitalLa Porte, Indiana  46350
Saint Joseph Regional Medical Center-MishawakaMishawaka, Indiana  46545-1470
Essentia Health Cancer Center-South University ClinicFargo, North Dakota  58103
PeaceHealth Saint Joseph Medical CenterBellingham, Washington  98225
Group Health Cooperative of Puget Sound Oncology ConsortiumSeattle, Washington  98109
Christiana Care Health System-Christiana HospitalNewark, Delaware  19718
Bronson Battle CreekBattle Creek, Michigan  49017
Springfield Regional Medical CenterSpringfield, Ohio  45505
The James Graham Brown Cancer Center at University of LouisvilleLouisville, Kentucky  40202
NEA Baptist Memorial HospitalJonesboro, Arkansas  72401
Marin Cancer Care IncGreenbrae, California  94904
Edward Hospital/Cancer CenterNaperville, Illinois  60540
Saint Louis Cancer and Breast Institute-South CitySaint Louis, Missouri  63109
Toledo Clinic Cancer Centers-Bowling GreenBowling Green, Ohio  43402
Toledo Clinic Cancer Centers-MaumeeMaumee, Ohio  43537-1839
Toledo Clinic Cancer Centers-ToledoToledo, Ohio  43623
PinnacleHealth Fox Chase Regional Cancer Center at Polyclinic HospitalHarrisburg, Pennsylvania  17110
Guthrie Clinic-Robert Packer HospitalSayre, Pennsylvania  18840
Self Regional HealthcareGreenwood, South Carolina  29646
Harrison Poulsbo Hematology and OncologyPoulsbo, Washington  98370
Aurora Cancer Care-Southern LakesElkhorn, Wisconsin  53121
Norris Cotton Cancer Center-NorthSaint Johnsbury, Vermont  05819
IU Health Ball Memorial HospitalMuncie, Indiana  47303
Sutter Pacific Medical FoundationSanta Rosa, California  95403
Halifax Health Medical Center-Centers for OncologyDaytona Beach, Florida  32114
Christus Saint Frances Cabrini HospitalAlexandria, Louisiana  71301
Maine Center for Cancer Medicine and Blood Disorders-ScarboroughScarborough, Maine  04074
Park Ridge Hospital Breast Health CenterHendersonville, North Carolina  28792
Holy Redeemer Hospital and Medical CenterMeadowbrook, Pennsylvania  19046
Blue Ridge Medical Specialists PCBristol, Tennessee  37620
NEA Baptist Clinic-MatthewsJonesboro, Arkansas  72401
Saint Luke's Mountain States Tumor Institute-Twin FallsTwin Falls, Idaho  83301
Ochsner Baptist Medical CenterNew Orleans, Louisiana  70115
Carolinas Medical Center-UnionMonroe, North Carolina  28112
Cleveland Regional Medical CenterShelby, North Carolina  28150
Cancer Center of Western WisconsinNew Richmond, Wisconsin  54017
Kaiser Permanente Tysons Corner Medical CenterMcLean, Virginia  22102
Mercy Cancer Center-West LakesClive, Iowa  50325
Mercy Medical Center-West LakesWest Des Moines, Iowa  50266
Saint Clare's HospitalWeston, Wisconsin  54476
D N Greenwald CenterMukwonago, Wisconsin  53149
Swedish Medical Center-EdmondsEdmonds, Washington  98026
Rex Cancer Center of WakefieldRaleigh, North Carolina  27614
Breastlink Medical Group IncLong Beach, California  90806
Texas Oncology PA - BedfordBedford, Texas  76022
Cancer Care Centers of South Texas- NortheastSan Antonio, Texas  78217
Kaiser Permanente-ModestoModesto, California  95356
Arizona Oncology Associates-Biltmore Cancer CenterPhoenix, Arizona  85016
Kaiser Permanente-Capitol Hill Medical CenterWashington, District of Columbia  20002
Penobscot Bay Medical CenterRockport, Maine  04856
Kaiser Permanente-Woodlawn Medical CenterBaltimore, Maryland  21244
Kaiser Permanente-Gaithersburg Medical CenterGaithersburg, Maryland  20879
Southcoast Centers for Cancer Care-FairhavenFairhaven, Massachusetts  02719
Saint Peters Hospital-AlbanyAlbany, New York  12208
Mercy Suburban Cancer CenterNorristown, Pennsylvania  19401
Wellmont Bristol Regional Medical CenterBristol, Tennessee  37620
Hendrick Medical CenterAbilene, Texas  79601
Texas Cancer Center - Medical City DallasDallas, Texas  75230
Texas Oncology-El PasoEl Paso, Texas  79915
Texas Oncology-Flower MoundFlower Mound, Texas  75028
Texas Oncology Fort Worth at 12th AvenueFort Worth, Texas  76104
Texas Oncology-McAllenMcAllen, Texas  78503
Hematology Oncology Association of San Antonio TexasSan Antonio, Texas  78229
US Oncology Research LLC-The WoodlandsThe Woodlands, Texas  77380
Kaiser Permanente-Burke Medical CenterBurke, Virginia  22015