Is there a genetic link between breast and pancreatic cancer?

No

No

Actually Dr Benedetto that is not correct. The same gene in women with Breast Cancer - BRCA2 gene on chromosome 13q is inactivated in fewer than 10 percent of pancreatic cancers. The gene is almost always inactivated by a germline inhereted mutation coupled with somatic loss of the second allele. Germline mutations in BRCA2 (one of the causes of the hereditary breast and ovarian cancer syndrome) are associated with an increased risk of pancreatic cancer. This constitutes one of the most important causes of familial aggregation of pancreatic cancer. BRCA2 mutations are found in up to 17 percent of patients with familial pancreatic cancer.

Actually Dr Benedetto that is not correct. The same gene in women with Breast Cancer - BRCA2 gene on chromosome 13q is inactivated in fewer than 10 percent of pancreatic cancers. The gene is almost always inactivated by a germline inhereted mutation coupled with somatic loss of the second allele. Germline mutations in BRCA2 (one of the causes of the hereditary breast and ovarian cancer syndrome) are associated with an increased risk of pancreatic cancer. This constitutes one of the most important causes of familial aggregation of pancreatic cancer. BRCA2 mutations are found in up to 17 percent of patients with familial pancreatic cancer.