Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center founded in 1898 by Dr. Roswell Park. His revolutionary model of a “multidisciplinary approach” to cancer – with scientists and clinicians working in concert and in consult – has become the standard by which all modern-day comprehensive cancer centers are measured. RPCI is among the first and only upstate New York facility to hold the National Cancer Institute designation of "comprehensive cancer center" and to serve as a member of the prestigious National Comprehensive Cancer Network. Many RPCI faculty serve on the NCCN panels that create the Clinical Practice Guidelines in OncologyTM – the internationally recognized standards for clinical policy in oncology, and the most comprehensive, most frequently updated clinical practice guidelines available in any area of medicine. Over its long history, Roswell Park Cancer Institute has made fundamental contributions to reducing the cancer burden and has successfully maintained an exemplary leadership role in setting the national standards for cancer care, research and education.