Inclusion Criteria:

Any patient with a cancerous disease for which PET scan is indicated in the SOR (Standards
- Options - Recommendations) FDG PET 2003 updated in 2006 must be included in the trial,
in the following locations:

1. Digestive cancers

- Colorectal cancer

- Preoperative evaluation in local and metastatic recurrence

- Location of recurrences, in case of ACE increase in a previously operated
patient.

- Esophageal cancer: initial staging.

- Pancreatic cancer

- Initial staging,

- Differential diagnosis with chronic pancreatitis.

- Liver cancer: differential diagnosis of liver metastases, cholangiocarcinoma and
benign tumors in the case of an isolated hepatic localization.

- Digestive Endocrine tumors: staging in case of normal pentetreotide
scintigraphy.

2. Lung cancer

- Initial staging,

- Diagnosis of lung isolated lesion > 1 cm.

3. Head and neck cancer

- Initial pretreatment staging,

- Recurrence diagnosis

4. Lymphoma

- Initial staging of Hodgkin's disease (HD), non-Hodgkin's lymphoma (NHL) and
aggressive follicular lymphomas,

- Diagnosis of minimal residual disease of HD and aggressive NHL,

- Early assessment of treatment response.

5. Thyroid cancer: suspicion of residual disease or relapse when conventional imaging
data are insufficient.

6. Ovarian cancer recurrence

7. Age ≥ 18 years.

8. Chest-abdomen-pelvis enhanced CT scan achieved within 4 weeks before enrollment (with
cuts of less than 5 mm).

9. Woman of childbearing age with negative pregnancy test and / or contraception.

10. Patient with informed consent signed.

11. Patient affiliated to social security schemes.

Exclusion Criteria:

1. Iodine known allergy.

2. Diabetes, excepted if controlled (hemoglucotest ≤ 1.6 g).

3. Known renal failure (creatinine clearance <60ml/min).

4. Indications against Xenetix ®:

- Hypersensitivity to Xenetix ® or any of the excipients,

- History of an immediate response or delayed cutaneous reaction to Xenetix ®
injection.

- Thyrotoxicosis.

5. Pregnant or lactating women.

6. Unable to undergo medical follow up for geographical, social or psychological
reasons,

7. Private of freedom patient and adult under a legal guardianship or unable to consent.