Inclusion Criteria:

- Age ≥ 18 years

- Patients with thyroid nodules ≥ 15 mm with an indeterminate cytology (IC) older than
6 months, for which a surgical indication was raised

- vesicular lesion of undetermined significance

- follicular neoplasm or Hurthle cells

- lesion suspicious for malignancy

- Confirmation of indeterminate cytology (IC) replay centralized

- Patient affiliated to a social security scheme

- Informed consent and signed

Exclusion Criteria:

- Thyroid node <15 mm

- Nodules coalescing preventing proper individualization of targeted nodule

- Indeterminate cytology older than six months

- Nodules with indeterminate cytology not, ie non-diagnostic cytology, benign and
malignant cytology cytology

- Major subject to a measure of legal protection or unable to consent

- Refusal to participate