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PHARMACOGENETICS OF VINORELBINE IN MALIGNANT PLEURAL MESOTHELIOMA PATIENTS


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Open (Enrolling)
Both
Malignant Pleural Mesothelioma Patients Treated With Vinorelbine as a Second or Later Line Chemotherapy

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Trial Information

PHARMACOGENETICS OF VINORELBINE IN MALIGNANT PLEURAL MESOTHELIOMA PATIENTS


Inclusion Criteria:



- MPM patients treated with vinorelbine in the ≥ second line setting will be
retrospectively analyzed

- Patients will be selected based on the availability of tumor tissue

Exclusion Criteria:

- NA

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Retrospective

Outcome Measure:

Expression of TUBB3 and BRCA1 in MPM tumor tissue by immunohistochemistry and RT-PCR.

Outcome Time Frame:

2 months

Safety Issue:

No

Principal Investigator

armando santoro, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Istituto Clinico Humanitas

Authority:

Italy: Ministry of Health

Study ID:

ONC/OSS-02/2012

NCT ID:

NCT01865045

Start Date:

November 2012

Completion Date:

May 2014

Related Keywords:

  • Malignant Pleural Mesothelioma Patients Treated With Vinorelbine as a Second or Later Line Chemotherapy
  • Mesothelioma

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