Know Cancer

or
forgot password

Prevention of Ovarian Cancer in Women Participating in Mammography


N/A
35 Years
N/A
Open (Enrolling)
Female
Epithelial Ovarian Cancer

Thank you

Trial Information

Prevention of Ovarian Cancer in Women Participating in Mammography


Inclusion Criteria:



- Prior mammogram at Swedish Medical Center

- Willing and able to provide informed consent, primary physician information, and
complete study questionnaires

- Must meet at least ONE of the following criteria:

- personal history of breast cancer diagnosed before age 50

- personal history of bilateral breast cancer at any age

- 1 or more first degree relatives with breast cancer diagnosed before age 50

- 3 or more first or second degree relatives with breast cancer at any age

- 2 second degree relatives with breast cancer diagnosed before age 50

- A male relative with breast cancer at any age

- Ashkenazi Jewish with any family history of breast or ovarian cancer

- 1 first or second degree relative with ovarian cancer AND 1 first or second degree
relative with breast cancer at any age

- 2 first degree relatives with ovarian cancer or 2 second degree relatives with
ovarian cancer or 1 first and 1 second degree relative with ovarian cancer.

- A first degree relative with both breast and ovarian cancer (2 primaries in the same
person)

- Personal history of positive genetic test result for any of the following genes:
BRCA1, BRCA2, HNPCC, or P53

- Family history of a positive genetic test result for any of the following genes:
BRCA1, BRCA2 or HNPCC

Exclusion Criteria:

- Previous diagnosis of ovarian cancer

- Prior bilateral-salpingo oophorectomy

- Had a negative genetic test result for a known family genetic mutation

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Prevention

Outcome Measure:

Compare rates of risk-reducing salpingo-oophorectomy in each of the study arms

Outcome Time Frame:

24 months post-enrollment

Safety Issue:

No

Principal Investigator

Nicole Urban, ScD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Fred Hutchinson Cancer Research Center

Authority:

United States: Institutional Review Board

Study ID:

1R18DP001142-01

NCT ID:

NCT01851109

Start Date:

July 2008

Completion Date:

May 2013

Related Keywords:

  • Epithelial Ovarian Cancer
  • ovarian cancer
  • prevention
  • prophylactic surgery
  • risk
  • biomarkers
  • screening
  • symptoms
  • Ovarian Neoplasms
  • Neoplasms, Glandular and Epithelial

Name

Location

Fred Hutchinson Cancer Research CenterSeattle, Washington  98109