Trial Information
A Randomized Controlled Trial of the Effectiveness of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer
Inclusion Criteria:
- >18 years old
- They had a histological diagnosis of papillary, follicular, medullary or anaplastic
thyroid cancer
- They had undergone total thyroidectomy
- They were able to provide consent
Exclusion Criteria:
- patients who had distant metastases,
- a history of salivary-gland disorders,
- collagen tissue disease
- diabetes mellitus,
- previous radioiodine therapy or external radiation to the head or neck
- allergy to the honey
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Single Blind (Investigator), Primary Purpose: Prevention
Outcome Measure:
Grade of sialadenitis
Outcome Time Frame:
Change from Baseline grade of sialadenitis at 6 and 24 months
Safety Issue:
No
Principal Investigator
Andreas Charalambous, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Cyprus University of Technology
Authority:
Cyprus: Bank of Cyprus Oncology Center Research Committee
Study ID:
AC-HCS-89
NCT ID:
NCT01833650
Start Date:
May 2013
Completion Date:
September 2014
Related Keywords:
- Thyroid Cancer
- thyroid cancer
- radioiodine treatment
- xerostomia
- sialadenitis
- Thyroid Neoplasms
- Thyroid Diseases