Trial Information

Self Reported Changes in Quality of Life, Sexual Function, Peripheral Neuropathy, and Demands of Illness, Following Curative Resection and Adjuvant FOLFOX Chemotherapy in Colon Cancer Survivors

The prospective design with three cohorts of participants will describe the changes in
quality of life, sexual function, peripheral neuropathy and demands of illness following
curative resection and adjuvant chemotherapy (Aims 1-4). An analysis of the interaction
between time (four measurement occasions) and surgical type (open resection, laparoscopic
resection, robotic resection) by mean values of quality of life, sexual function, peripheral
neuropathy, and demands of illness will examine the central thesis question (Aim 5).

Specific Aims

1. Describe the demographic and disease characteristics of the sample.

2. Examine the relationships among quality of life, sexual functioning, peripheral
neuropathy, and demands of illness for the sample-as-a-whole and by type of surgical
resection (open, laparoscopic, robotic).

3. Examine within-subject changes in the mean values of scores for quality of life, sexual
functioning, peripheral neuropathy, and demands of illness across four measurement
occasions.

4. Examine between-group differences in mean values of scores for quality of life, sexual
function, peripheral neuropathy, and demands of illness at four discrete measurement
occasions.

5. Examine the interaction between time (four measurement occasions) and surgical type
(open resection, laparoscopic resection, robotic resection) by mean values of quality
of life, sexual function, peripheral neuropathy, and demands of illness.