A Biobehavioral Intervention for Patients With Gynecologic or Breast Cancer Recurrence
I. To refine the intervention. II. Test the acceptability, feasibility, and clinical
appropriateness of the intervention.
III. To provide a preliminary test of its efficacy.
Patients participate in a multi-component intervention based on cognitive and behavioral
principles comprising mindfulness-based stress reduction (MBSR), an intervention to promote
hopefulness, and a problem solving approach which navigates around obstacles or generates
alternatives when goals become blocked. Additional topics may be covered as indicated by
clinical need and patients goals. Biobehavioral components include addressing social and
disease-specific quality of life, and pain education. Intensive treatment sessions continue
weekly for 16 weeks followed by 2 biweekly and 2 monthly maintenance sessions.
After completion of study treatment, patients are followed up at 28 weeks.
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Quality of life as assessed by Short Form (SF)-36
up to 28 weeks
Barbara Andersen, PhD
Ohio State University Comprehensive Cancer Center
United States: Institutional Review Board
|Ohio State University Medical Center||Columbus, Ohio 43210|