Pilot Study of Geriatric Assessments in Senior Adults With Multiple Myeloma
Time Perspective: Prospective
Frequencies will be tabulated for categorical variables initial treatment strategy with and without HDT/ASCT. Prevalence of comorbidity and dependencies in Instrumental Activities of Daily Living (IADLs) at baseline in these two groups will be reported with 95% confidence intervals. Univariate analysis will be performed to compare the comorbidity and dependencies in IADLs at baseline in patients whose initial treatment strategy with and without HDT/ASCT. These analyses will be conducted using the χ2 test for proportions and pooled t test for continuous variables. In the planned multivariate analysis, no more than 2 variables will be entered into the multivariate model, given the sample size of 30. Variables significant at a p<0.20 level on univariate analysis will move forward in the multivariate model.
Tanya Wildes, M.D.
Washington University School of Medicine
United States: Institutional Review Board
|Washington University School of Medicine||Saint Louis, Missouri 63110|