Inclusion Criteria:

- Age 30 - 60 year old men

- Willingness to be randomized to resveratrol or placebo.

- BMI 30-40

- Evidence of insulin resistance with one of the following:

2 hr oral glucose tolerance result =/>120mg/dl at 2hrs acanthosis nigricans, or HgA1C
5.7 - 7.9% AND at least 2 of the following: waist circumference > 102 cm
triglycerides > 150 but < 500 mg/dL HDL < 40 mg/dL Pre- hypertension or hypertension:
BP>120/80 mmHg but <150/90 mmHg

- Willingness to consume only study food and drink during the in-pt phases

- Willingness to avoid the use of over-the-counter medications, herbs, or supplements
within the last 30 days.

- Willingness to avoid NSAIDS (advil, aleve, motrin, etc.) and aspirin for the entire
study

- Willingness to avoid ingestion of any foods containing peanuts, bilberries,
blueberries, cranberries, strawberries, raspberries, grapes, grape juice, cocoa
powder, dark chocolate, and red wine throughout the entire study, including run-in
period.

- Willingness to maintain weight for the duration of the study.

- Willingness not to start an exercise regime during study participation

Exclusion Criteria:

- Tobacco smoker any time within the last 3 months

- Bleeding disorder by history or by Bleeding Questionnaire results

- History, physical or EKG findings suggestive of CV disease including angina, MI, hx
of med/surg tx of atherosclerotic heart disease, or congestive heart disease

- BP > 145/90 after 10 minutes of rest on 2 or more screening visits

- Fasting glucose > 165 mg/dL at screening

- HbA1C > 8.0 at screening

- Current use of oral hypoglycemic agents

- Chronic glucocorticosteroid use or use of oral glucocorticosteroids for 5 days within
the last year (inhaled glucocorticosteroid use may be acceptable; this will be
determined by the PI)

- Current use of over the counter or prescription weight loss medication

- Current use or within the last 30 days, any cholesterol lowering medications
(statins, fibrates, red yeast rice, niacin).

- Hyperthyroidism or untreated hypothyroidism

- Obstructive sleep apnea, or significant symptoms suggestive of this condition.

- Current use of anticoagulants

- Known history of chronic hepatitis or liver enzymes (ALT or AST > 2.5 times the
normal upper limit)

- Known HIV infection or confirmed positive test for HIV antibodies at screening

- Inflammatory bowel disease

- Active cancer (currently under treatment)

- Other medical condition that may cause significant weight loss or gain

- Chronic or acute renal disease

- Seizure disorder

- History of any psychiatric hospital admission within the last 2 years

- History of schizophrenia, psychosis, or bipolar disease

- History, physical, social or lab findings suggestive of any medical or psychological
condition that would, in the opinion of the PI, impact the subject's ability to
successfully participate in the study.

- Alcohol or drug abuse within the last 2 years

- Any medications metabolized by cytochrome p450 3A4 (CYPA3A4) (see attachment of
these medications as an appendix)

- Any autoimmune disease (ie rheumatoid arthritis, systemic lupus erythematosis,
psoriasis)

- Physical condition requiring special diet (ie celiac disease)