Inclusion Criteria:

- Histologically or cytologically (if cannot be proven histologically, at least twice
positive findings on fine needle aspiration or sputum cytology) confirmed SCLC

- Limited stage (Clinical stage I-IIIb, lesion limited to one side of thorax, e.g.
Excluding T4 disease with malignant pleural effusion or N3 disease with contralateral
hilum/supraclavicular lymph node invasion).

- Measurable or assessable lesion

- Age over 18 years old

- Performance status (ECOG scale): 0~2

- Adequate organ functions: ANC ≥ 1500/ul, PLT ≥ 100 x 103/u, Total Bilirubin ≤ 1.5
mg/dl, Creatinine ≤ 1.5 mg/dl

- Inclusion of tumor within the limited radiation field without significant loss of
pulmonary function (confirmed by radiation oncologist)

- Sexually active fertile men and women using a contraceptive method

- Patients should sign a written informed consest before study entry

Exclusion Criteria:

- T4 disease with malignant pleural effusion; N3 disease with contralateral
hilum/supraclavicular lymph node invasion

- Lesion with mixed small cell nonsmall cell feature (pathologically)

- prior chemotherapy or radiation therapy.

- Pericardial or pleural effusion on chest X-ray image regardless of cytological
finding

- T4 disease with tumor invasion to great vessels, heart, trachea, or esophagus;
Concerns about possible perforation by tumor necrosis

- Severe comorbidities such as cardiac disease with symptom, myocardiac infarction
within 6 months, chronic obstructive pulmonary disease with FEV1 less than 1.0ℓ, or
uncontrolled bronchospasm of unaffected lung

- With atelectasis that makes GTV unidentifiable

- Other primary malignancy (except in situ carcinoma of the cervix or adequately
treated basal cell carcinoma of the skin or prior malignancy treated more than 3
years ago without recurrence)

- Uncontrolled psychiatric disorder, serious head injury, chronic alcoholism, drug
addiction and central nervous system disease