A Pilot Randomized Controlled Trial Examining the Differences of Quality of Life of Roux-En-Y Pouch Reconstruction and Conventional Roux-En-Y Reconstruction in Patients Undergoing Total Gastrectomy.
Total gastrectomy has been indicated mainly for advanced gastric cancer located from the
upper to middle third of the stomach or multiple gastric cancers.The most common method of
creating a way for food is called a "Roux-en-Y", in which one part of the intestines is
connected with the end of the esophagus (the swallowing tube) in the abdomen, and another
connection is made between the intestines ' lower down.
Patients with total gastrectomy suffer from poor food intake, anemia, and poor digestion
because of loss of gastric reservoir or a lack of normal hormonal secretion for digestion.
It often is associated with a limitation of postoperative quality of life (QOL). To improve
postoperative nutritional status and QOL, surgeons have tried to establish ideal
reconstruction after total gastrectomy and the optimum procedure for reconstruction has been
This study will compare the postoperative quality of life (QOL) of gastric pouch
reconstruction with the usual reconstruction to see if the pouch makes patients feel better.
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Change in QOL (Quality of Life)
From preoperative following total gastrectomy, as measured with the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQ-STO22 questionnaires
China: Food and Drug Administration