Know Cancer

forgot password

Helping Cancer Patients Quit Smoking by Improving Their Risk Communication: a Cluster Randomized Controlled Trial

18 Years
Not Enrolling
Cancer, Smoking Cessation

Thank you

Trial Information

Helping Cancer Patients Quit Smoking by Improving Their Risk Communication: a Cluster Randomized Controlled Trial

Smoking causes many types of cancer in general. Past studies have shown that current smokers
have increased risk of cancer, and most lung cancers are attributable to smoking. Cancer
(malignant neoplasm) is the number one killer in Hong Kong, which leads to nearly one-third
of all deaths each year. Cancer patients who continue smoking would result in extra risks of
all cause mortality, cancer recurrence and second primary cancer as well as reducing
survival time (Chen et al., 2010). Smoking could also reduce the efficacy of clinical and
medical treatment of cancer including radio- and chemo-therapies (Benninger et al., 1994;
Browman et al., 1993) and increase the risk of treatment related side-effects (Rugg et al.,

Cancer patients may present an excellent "teachable moment" for smoking cessation
interventions, as their current illness could largely be due to smoking. However, few
smoking cessation programs target on this vulnerable group and only one-third of oncology
nurses would assist cancer patients quit smoking. Healthcare professionals have the
responsibility to assist this vulnerable group to quit smoking. Recent randomized controlled
trials (RCT) suggested behavioral intervention may help cancer patients quit smoking, but
they are limited by small sample size. No RCT study has ever been done in Hong Kong.

This study can make an important contribution to evidence-based practice by testing the
effectiveness of a tailored smoking cessation intervention targeting cancer patients. The
results primarily serve the purpose to support the development of clinical practice
guidelines and interventions to promote smoking cessation in cancer patients to improve
their cancer prognosis and, in the long-run, increase their survival time and quality of

Inclusion Criteria:

- Cancer patients smoked weekly in the past 6 months;

- patients in all stages 0,I,II,III, or IV;

- aged 18 or above; and

- can communicate in Cantonese

Exclusion Criteria:

- those with unstable medical conditions as advised by the doctor in charge;

- poor cognitive state or with mental illness; and

- those participating in other smoking cessation program.

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Outcome Measure:

The self-reported 7-day point prevalence (pp) quit rate at the sixth month

Outcome Description:

Whether the participant has quitted smoking in the past seven days at the time point of 6 months

Outcome Time Frame:

Six months

Safety Issue:


Principal Investigator

Sophia SC Chan, PhD, MPH

Investigator Role:

Principal Investigator

Investigator Affiliation:

The University of Hong Kong


Hong Kong: Hospital Authority

Study ID:




Start Date:

September 2012

Completion Date:

August 2015

Related Keywords:

  • Cancer
  • Smoking Cessation
  • Cancer patients
  • Smoking cessation
  • Risk communication
  • Smoking