Know Cancer

or
forgot password

Development of a Risk Model Predicting Chemotherapy-induced Grade 3-4 Neutropenia by Paclitaxel/Carboplatin in Epithelial Ovarian Cancer: Prospective Observational Study for Model Development and Retrospective Study for Validation of Developed Model


N/A
20 Years
80 Years
Open (Enrolling)
Female
Epithelial Ovarian Cancer

Thank you

Trial Information

Development of a Risk Model Predicting Chemotherapy-induced Grade 3-4 Neutropenia by Paclitaxel/Carboplatin in Epithelial Ovarian Cancer: Prospective Observational Study for Model Development and Retrospective Study for Validation of Developed Model


Inclusion Criteria:



- Patients with FIGO stage I-IV epithelial ovarian cancer after staging or debulking
surgery

- Patients who is planned to receive (prospective cohort) ro who received
(retrospective cohort) adjuvant chemotherapy with paclitaxel and carboplatin

- Patients who have signed approved informed consent

Exclusion Criteria:

- Uncontrolled medical disease

- Active infectious disease

- Previous pelvic radiation therapy

- Previous chemotherapy (prospective cohort)

- Patients with disease which can cause neutropenia

- Patients who will receive other targeted therapy or immunotherapy during adjuvant
therapy (prospective cohort).

- Pregnant or lactating woman

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Risk prediction model for grade 3-4 chemotherapy induced neutropenia

Outcome Time Frame:

1 year

Safety Issue:

No

Principal Investigator

Jeong-Yeol Park, M.D., Ph.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Asan Medical Center

Authority:

Korea: Asan Medical Center Institutional Review Board

Study ID:

NEPACA-OVCA

NCT ID:

NCT01680575

Start Date:

September 2012

Completion Date:

Related Keywords:

  • Epithelial Ovarian Cancer
  • Neutropenia
  • Paclitaxel
  • Carboplatin
  • Epithelial ovarian cancer
  • Neutropenia
  • Ovarian Neoplasms
  • Neoplasms, Glandular and Epithelial

Name

Location