THE ROLE OF FLOSEAL IN THE PREVENTION OF LYMPHOCELE AND LYMPHATIC ASCITES AFTER LYMPH NODE DISSECTION FOR GYNECOLOGIC CANCER: A RANDOMIZED CONTROLLED TRIAL
Inclusion Criteria:
- Histologically confirmed primary cancer of the uterine cervix, uterine corpus, ovary,
and fallopian tube
- FIGO stage Cervical cancer: FIOG stage IA2-IIA2 Uterine cancer: FIGO stage I-III
Ovarian and fallopian tubal cancer: FIGO stage I-IIIB
- Patients who undergoing surgery including pelvic and/or para-aortic lymph node
dissection
- Patients with adequate bone marrow, renal and hepatic function:
WBC > 3,000 cells/mcl Platelets >100,000/mcl Creatinine <2.0 mg/dL Bilirubin <1.5 x normal
and SGOT or SGPT <3 x normal
- American Society of Anesthesiology Physical Status 0-1
- Performance status of ECOG 0-2
- Patient must be suitable candidates for surgery
- Patients who have signed an approved Informed Consent
Exclusion Criteria:
- Patients with a history of pelvic or abdominal radiotherapy;
- Patients who are pregnant
- Patients with contraindications to surgery;
- Patients who are unfit for Surgery: serious concomitant systemic disorders
incompatible with the study (at the discretion of the investigator);
- Patient's compliance and geographic proximity that do not allow adequate follow-up.
- Patients who undergo only lymph node sampling