A Phase I Dose-Escalation Study of Cisplatin and Radiation Therapy for Patients With Triple Negative Breast Cancer
This is a phase I dose escalation study of cisplatin and radiation to determine the
toxicity of this combined treatment and establish an MTD.
Interventional
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Safety of Cisplatin w/ Radiation
To determine the maximum tolerated dose of cisplatin when given concurrently with radiation therapy for participants with Stage II or III breast cancer who have undergone breast conserving surgery.
2 years
Yes
Jennifer R Bellon, MD
Principal Investigator
Dana-Farber Cancer Institute
United States: Food and Drug Administration
12-283
NCT01674842
October 2012
October 2017
Name | Location |
---|---|
Dana-Farber Cancer Institute | Boston, Massachusetts 02115 |
Brigham and Women's Hospital | Boston, Massachusetts 02115 |