The Value of Mesenchymal Black Spots in Diagnosing Gastric Intestinal Metaplasia by Confocal Laser Endomicroscopy
18 Years
80 Years
Both
Gastric Intestinal Metaplasia
Trial Information
The Value of Mesenchymal Black Spots in Diagnosing Gastric Intestinal Metaplasia by Confocal Laser Endomicroscopy
Gastric intestinal metaplasia (GIM) is confirmed to be a risk factor that may lead to the
development of intestinal type gastric cancer. Previous study has shown that confocal laser
endomicroscopy promising in the diagnosis of GIM. The investigators have found an elevated
incidence of mesenchymal black spots in patients with GIM during previous CLE imaging. This
study aims to explore the properties of mesenchymal black spots, and to determine the value
of mesenchymal black spots in diagnosing gastric intestinal metaplasia by confocal laser
endomicroscopy.
Inclusion Criteria:
- Patients will include male or female aged between 18 and 80 years with
indications for upper-endoscopy , but without any disease of heart, liver or kidney.
Exclusion Criteria:
- Patients who are allergic to fluorescein sodium
- Patients who are unwilling to sign or give the informed consent form
- Patients with impaired cardiac, liver or renal function
- Patients with coagulopathy
- Patients with pregnancy or breastfeeding
Type of Study:
Observational
Study Design:
Time Perspective: Prospective
Outcome Measure:
Accuracy of black spots in diagnosis of gastric intestinal metaplasia
Outcome Time Frame:
up to six months
Safety Issue:
No
Principal Investigator
Yanqing Li, MD, PhD
Investigator Role:
Study Director
Investigator Affiliation:
Department of Gastroenterology, Qilu Hospital
Authority:
China: Ministry of Health
Study ID:
2012SDU-QILU-G01
NCT ID:
NCT01646528
Start Date:
June 2012
Completion Date:
December 2012
Related Keywords:
- Gastric Intestinal Metaplasia
- Gastric Intestinal Metaplasia
- Confocal Laser Endomicroscopy
- Metaplasia
- Gastritis, Atrophic
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