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Cancer Biology of Retinoblastoma


N/A
N/A
5 Years
Open (Enrolling)
Both
Retinoblastoma

Thank you

Trial Information

Cancer Biology of Retinoblastoma


Inclusion Criteria:



- Patient must have retinoblastoma

- Patient must be receiving biopsy, partial surgical excision of the tumor, complete
excision of the tumor, or enucleation of the eye as part of their standard care.

- Parental consent

Exclusion Criteria:

- Diagnosis other than Retinoblastoma

- No surgical sampling of tumor is planned as part of standard care

- Parental preference to not participate.

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Retrospective

Outcome Measure:

Change in efficiency of reprogramming in cells with "naturally occurring" retinoblastoma mutations

Outcome Description:

Comparison of number of reprogramming events (defined by colony formation assay and normalized for number of cell plated) as well as the time to reprogramming.

Outcome Time Frame:

After appropriate time, e.g., 7, 10, 14 days after reprogramming

Safety Issue:

No

Principal Investigator

Phillip Garfin

Investigator Role:

Principal Investigator

Investigator Affiliation:

Stanford University

Authority:

United States: Institutional Review Board

Study ID:

PEDSEYE0002

NCT ID:

NCT01642823

Start Date:

July 2012

Completion Date:

December 2017

Related Keywords:

  • Retinoblastoma
  • retinoblastoma
  • Retinoblastoma

Name

Location

Stanford University Cancer InstituteStanford, California  94305